Accelerated aging is characteristic for patients with type 1 diabetes mellitus (DM1), so manifestations are not only in the increased frequency of cardiovascular events, but also in decreasing of ovarian-menstrual function, in the earlier onset of menopause. It has been shown that the decreasing of the reproductive function in patients with CD1 may be associated, in particular, with a decrease in the ovarian reserve. Premature aging are frequently observed among individuals with type 1 diabetes. Decrease of ovarian reserve may be one of the characteristics of such process. Objective — to evaluate the ovarian reserve function in female patients of reproductive age with type 1 diabetes in comparison with healthy women. Material and methods. This study evaluated 224 Caucasian women, age 20—30 years with type 1 diabetes and 230 healthy women of comparable age. Anthropometrics, serum concentrations of anti-Mullerian hormone (AMH), inhibin B, follicle stimulating hormone (FSH), luteinizing hormone (LH), estradiol, progesterone, and testosterone were compared on the 2—3 day of menstrual cycle as ovarian volume and antral follicle count (AFC). In addition, glycated hemoglobin level (HbA1c) and count of a CGG repeat in FMR1 gene was evaluated. Results. We reveal statistically significant difference in following parameters in diabetic women in comparison with healthy women: AMH, AFC and HbA1c. But even in diabetic patients parameters remained within reference ranges. There was strong negative correlation between HbA1c and AMG levels. There were no differences between count of a CGG repeat in FMR1 gene in diabetic patients and healthy women. Conclusions. Ovarian reserve function parameters decrease in yang women with type 1 diabetes in comparison with healthy women, but ovarian reserve parameters are in normal reference range. These findings are important in pregnancy planning consulting by gynecologists and endocrinologists. We must recommend to women with type 1 diabetes more early planning of natural pregnancy for treatment with reproductive technology in cases of prolog absence of nature pregnancy.