Management and multifetal pregnancy reduction of higher-order multifetal pregnancy with monochorionic twin pairs

Pribushenia O.V.

GU "Respublikanskiĭ nauchno-prakticheskiĭ tsentr "Mat' i ditia" Ministerstva zdravookhraneniia Respubliki Belarus', Minsk

Kotova S.A.

GU "Nauchno-prakticheskiĭ tsentr Gosudarstvennogo komiteta sudebnykh kspertiz Respubliki Belarus'", Minsk, Belarus', 220053

Rybakova V.I.

«Scientific and Practical Centre of the State Committee of forensic examinations of Republic of Belarus», Minsk, Republic of Belarus, 220053

Tsybovskiĭ I.S.

GU "Nauchno-prakticheskiĭ tsentr Gosudarstvennogo komiteta sudebnykh kspertiz Respubliki Belarus'", Minsk, Belarus', 220053

Management and multifetal pregnancy reduction of higher-order multifetal pregnancy with monochorionic twin pairs

Authors:

Pribushenia O.V., Kotova S.A., Rybakova V.I., Tsybovskiĭ I.S.

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Journal: Russian Journal of Human Reproduction. 2016;22(6): 120‑125

DOI: 10.17116/repro2016226120-125

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Pribushenia OV, Kotova SA, Rybakova VI, Tsybovskiĭ IS. Management and multifetal pregnancy reduction of higher-order multifetal pregnancy with monochorionic twin pairs. Russian Journal of Human Reproduction. 2016;22(6):120‑125. (In Russ.)
https://doi.org/10.17116/repro2016226120-125

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We report our results of transabdominal multifetal pregnancy reduction in the first trimester of pregnancy by introtorax potassium chloride injection (n=19). We successfully made 14 reductions of one of monochorionic fetuses in dichorionic triamniotic triplet or trichorionic tetraamniotic quadruplet pregnancies. The fetus death rate of second monochorionic fetuses was 85,7±9,35% (n=12) fort 3 days or less postprocedure. Molecular-genetic analysis zygosity by short tandem repeats DNA (STR markers) was made for other 2 cases. We detected 2 monochorionic twin pairs were monozygotic. Multifetal pregnancy reduction is an efficient and safe way of improving outcome in high-order pregnancy, but risk of second fetus death of monochorionic fetuses is high.

Keywords:

multifetal pregnancy

quadruplet pregnancy

triplet pregnancy

multifetal pregnancy reduction

monochorionic

zygosity

molecular genetic analysis

microsatellite markers

Authors:

Pribushenia O.V.

GU "Respublikanskiĭ nauchno-prakticheskiĭ tsentr "Mat' i ditia" Ministerstva zdravookhraneniia Respubliki Belarus', Minsk

Kotova S.A.

GU "Nauchno-prakticheskiĭ tsentr Gosudarstvennogo komiteta sudebnykh kspertiz Respubliki Belarus'", Minsk, Belarus', 220053

Rybakova V.I.

«Scientific and Practical Centre of the State Committee of forensic examinations of Republic of Belarus», Minsk, Republic of Belarus, 220053

Tsybovskiĭ I.S.

GU "Nauchno-prakticheskiĭ tsentr Gosudarstvennogo komiteta sudebnykh kspertiz Respubliki Belarus'", Minsk, Belarus', 220053

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