Management and multifetal pregnancy reduction of higher-order multifetal pregnancy with monochorionic twin pairs

Pribushenia O.V.; Kotova S.A.; Rybakova V.I.; Tsybovskiĭ I.S.

doi:https://doi.org/10.17116/repro2016226120-125

Pribushenia O.V.

GU "Respublikanskiĭ nauchno-prakticheskiĭ tsentr "Mat' i ditia" Ministerstva zdravookhraneniia Respubliki Belarus', Minsk

Kotova S.A.

GU "Nauchno-prakticheskiĭ tsentr Gosudarstvennogo komiteta sudebnykh kspertiz Respubliki Belarus'", Minsk, Belarus', 220053

Rybakova V.I.

«Scientific and Practical Centre of the State Committee of forensic examinations of Republic of Belarus», Minsk, Republic of Belarus, 220053

Tsybovskiĭ I.S.

GU "Nauchno-prakticheskiĭ tsentr Gosudarstvennogo komiteta sudebnykh kspertiz Respubliki Belarus'", Minsk, Belarus', 220053

Management and multifetal pregnancy reduction of higher-order multifetal pregnancy with monochorionic twin pairs

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Pribushenia O.V., Kotova S.A., Rybakova V.I., Tsybovskiĭ I.S.

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Journal: Russian Journal of Human Reproduction. 2016;22(6): 120‑125

DOI: 10.17116/repro2016226120-125

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Pribushenia OV, Kotova SA, Rybakova VI, Tsybovskiĭ IS. Management and multifetal pregnancy reduction of higher-order multifetal pregnancy with monochorionic twin pairs. Russian Journal of Human Reproduction. 2016;22(6):120‑125. (In Russ.)
https://doi.org/10.17116/repro2016226120-125

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)

Использование инфографики авторами научных работ

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Abstract:

We report our results of transabdominal multifetal pregnancy reduction in the first trimester of pregnancy by introtorax potassium chloride injection (n=19). We successfully made 14 reductions of one of monochorionic fetuses in dichorionic triamniotic triplet or trichorionic tetraamniotic quadruplet pregnancies. The fetus death rate of second monochorionic fetuses was 85,7±9,35% (n=12) fort 3 days or less postprocedure. Molecular-genetic analysis zygosity by short tandem repeats DNA (STR markers) was made for other 2 cases. We detected 2 monochorionic twin pairs were monozygotic. Multifetal pregnancy reduction is an efficient and safe way of improving outcome in high-order pregnancy, but risk of second fetus death of monochorionic fetuses is high.

Keywords:

multifetal pregnancy

quadruplet pregnancy

triplet pregnancy

multifetal pregnancy reduction

monochorionic

zygosity

molecular genetic analysis

microsatellite markers

Authors:

Pribushenia O.V.

GU "Respublikanskiĭ nauchno-prakticheskiĭ tsentr "Mat' i ditia" Ministerstva zdravookhraneniia Respubliki Belarus', Minsk

Kotova S.A.

GU "Nauchno-prakticheskiĭ tsentr Gosudarstvennogo komiteta sudebnykh kspertiz Respubliki Belarus'", Minsk, Belarus', 220053

Rybakova V.I.

«Scientific and Practical Centre of the State Committee of forensic examinations of Republic of Belarus», Minsk, Republic of Belarus, 220053

Tsybovskiĭ I.S.

GU "Nauchno-prakticheskiĭ tsentr Gosudarstvennogo komiteta sudebnykh kspertiz Respubliki Belarus'", Minsk, Belarus', 220053

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References:

Pribushenya O.V., i dr. Redkii sluchai monozigotnoi monokhorial'noi diamnioticheskoi troini s vrozhdennymi porokami razvitiya u dvukh plodov (torakoomfalopagi s gigromoi shei). Problemy reproduktsii. 2011;17(6):93-98.
Pribushenya O.V., i dr. Monozigotnaya dikhorial'naya triamnioticheskaya troinya s vrozhdennym porokom serdtsa u odnogo iz monokhorial'nykh bliznetsov. Prenatal'naya diagnostika. 2013;13(3):207-210.
Blickstein I, Keith LC. Prenatal assessment of multiple pregnancy. Taylor &Francis Group NW: informa healthcare. 2007;240.
Pribushenya O.V., Lemeshevskaya T.V., Duvakina M.G. Ul'trazvukovoe issledovanie pri mnogoplodii. Obzor literatury i sobstvennye klinicheskie nablyudeniya. Reproduktsiya zdorov'ya v Belarusi. 2012;6(24):88-106.
Sato Y, et al. Incidences of Feto-Fetal Transfusion Syndrome and Perinatal Outcomes in Triplet Gestations with Monochorionic Placentation. Fetal Diagn Ther. 2016.
Peeva G, et al. Endoscopic Placental Laser Coagulation in Dichorionic and Monochorionic Triplet Pregnancies. Fetal Diagn Ther. 2016.
Kerenyi TD, Chitkara U. Selective birth in twin pregnancy with discordancy for Down's syndrome. N Engl J Med. 1981;304(25):1525-1527.
Bercowitz RL, et al. Selective reduction of multifetal pregnancies in the first trimester. N Engl J Med. 1988;318:1043-1047.
Dumez Y, Oury JF. Method for first trimester selective abortion in multiple pregnancy. Contrib Gynecol Obstet. 1986;15:50-53.
Sepulveda W, et al. The lambda sign at 10—14 weeks of gestation as a predictor of chorionicity in twin pregnancies. Ultrasound Obstet Gynecol. 1996;7(6):421-423.
Medvedev M.V. (red.). Prenatal'naya ekhografiya. M.: Real'noe vremya. 2005; 551.
PCR-based typing protocols. FBI Laboratory. Washington DC, 1994 December 12;4-9, 4-28.
www.appliedbiosystems.com
«AmpFlSTR Yfiler PCR Amplification Kit User's Manual (PN 4358101D)» Applied Biosystems. 2011.
Hoffmann C, et al. Diffusion MRI findings in monochorionic twin pregnancies after intrauterine fetal death. AJNR Am J Neuroradiol. 2013;34(1):212-216.
Weisz B, et al. Early detection by diffusion-weighted sequence magnetic resonance imaging of severe brain lesions after fetoscopic laser coagulation for twin-twin transfusion syndrome. Ultrasound Obstet Gynecol. 2014;44(1):44-49.