The effectiveness of contraceptive containing estradiol valerate in combination with dienogest in patients with polycystic ovary syndrome

Pestrikova T.Iu.

Kafedra akusherstva i ginekologii Dal'nevostochnogo gosudarstvennogo meditsinskogo universiteta, Khabarovsk

Sukhonosova E.L.

Dal'nevostochnyĭ gosudarstvennyĭ meditsinskiĭ universitet, Khabarovsk

Iurasova E.A.

Kafedra akusherstva i ginekologii Dal'nevostochnogo gosudarstvennogo meditsinskogo universiteta, Khabarovsk

The effectiveness of contraceptive containing estradiol valerate in combination with dienogest in patients with polycystic ovary syndrome

Authors:

Pestrikova T.Iu., Sukhonosova E.L., Iurasova E.A.

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Journal: Russian Journal of Human Reproduction. 2016;22(3): 115‑122

DOI: 10.17116/repro2016223115-122

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To cite this article:

Pestrikova TIu, Sukhonosova EL, Iurasova EA. The effectiveness of contraceptive containing estradiol valerate in combination with dienogest in patients with polycystic ovary syndrome. Russian Journal of Human Reproduction. 2016;22(3):115‑122. (In Russ.)
https://doi.org/10.17116/repro2016223115-122

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Objective - to study the therapeutic effect of hormonal contraceptive (estradiol valerate combined with dienogest) in cyclic mode in patients with polycystic ovary syndrome (hyperandrogenism + polycystic ovaries). Material and methods. 36 patients aged 22 to 31 years with symptoms of hyperandrogenism and menstrual irregularities were included in the study. Results. Hormonal contraceptive (estradiol valerate combined with dienogest), was used in continuous mode. Positive therapeutic effect on clinical manifestations of hyperandrogenism and reproductive system of patients with polycystic ovary syndrome was observed. The contraceptive effect was noticed in 100% of cases. Conclusion. The therapeutic effect of estradiol valerate combined with dienogest showed reduction of hyperandrogenism symptoms (acne, oily skin person); a statistically significant reduction in sonographic parameters of the ovaries.

Keywords:

polycystic ovary syndrome (phenotype - ovulatory dysfunction+hyperandrogenism + polycystic ovaries) hormonal contraceptive (estradiol valerate combined with dienogest)

Authors:

Pestrikova T.Iu.

Kafedra akusherstva i ginekologii Dal'nevostochnogo gosudarstvennogo meditsinskogo universiteta, Khabarovsk

Sukhonosova E.L.

Dal'nevostochnyĭ gosudarstvennyĭ meditsinskiĭ universitet, Khabarovsk

Iurasova E.A.

Kafedra akusherstva i ginekologii Dal'nevostochnogo gosudarstvennogo meditsinskogo universiteta, Khabarovsk

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