The disturbed gonadal differentiation: dysgenesis and ovotesticular disorder of sex formation

Morozov D.A.

Saratovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. V.I. Razumovskogo Roszdrava, NII fundamental'noĭ i klinicheskoĭ uronefrologii Saratovskogo GMU

Raĭgorodskaia N.Iu.

Saratovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. V.I. Razumovskogo Roszdrava, NII fundamental'noĭ i klinicheskoĭ uronefrologii Saratovskogo GMU

Bolotova N.V.

Saratovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. V.I. Razumovskogo Roszdrava, NII fundamental'noĭ i klinicheskoĭ uronefrologii Saratovskogo GMU

Pimenova E.S.

Research Centre of Children’s Health;
I.M. Sechenov First Moscow State Medical University, Moscow

Maslyakova G.N.

V.I. Razumovsky Saratov State Medical University», Saratov

Tsmokaliuk E.N.

Saratovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. V.I. Razumovskogo Roszdrava, NII fundamental'noĭ i klinicheskoĭ uronefrologii Saratovskogo GMU

The disturbed gonadal differentiation: dysgenesis and ovotesticular disorder of sex formation

Authors:

Morozov D.A., Raĭgorodskaia N.Iu., Bolotova N.V., Pimenova E.S., Maslyakova G.N., Tsmokaliuk E.N.

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Journal: Problems of Endocrinology. 2015;61(1): 31‑35

DOI: 10.14341/probl201561131-35

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To cite this article:

Morozov DA, Raĭgorodskaia NIu, Bolotova NV, Pimenova ES, Maslyakova GN, Tsmokaliuk EN. The disturbed gonadal differentiation: dysgenesis and ovotesticular disorder of sex formation. Problems of Endocrinology. 2015;61(1):31‑35. (In Russ.)
https://doi.org/10.14341/probl201561131-35

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The objective of the present study was differential diagnostics between ovotestis and gonadal dysgenesis, the choice of the gender and the surgical strategy for the treatment of abnormal sexual glands. Diagnostics of the disturbances of gonadal differentiation (DGD) requires morphological verification. The ovotesticular gonad is characterized by the presence of a mature ovarian tissue and a dysgenetic testicular component. The authors describe the surgical separation of the ovotestis with preservation of the segments represented by the mature ovarian tissue. The presence of immature ovarian elements in the testicular gonad is one of the signs of its dysgenesis. Such cases need to be treated by the surgical removal of dysgenetic gonads.

Keywords:

ovotestis

gonadal dysgenesis

separation of gonads

sex chromosome mosaicism

Authors:

Morozov D.A.

Saratovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. V.I. Razumovskogo Roszdrava, NII fundamental'noĭ i klinicheskoĭ uronefrologii Saratovskogo GMU

Raĭgorodskaia N.Iu.

Saratovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. V.I. Razumovskogo Roszdrava, NII fundamental'noĭ i klinicheskoĭ uronefrologii Saratovskogo GMU

Bolotova N.V.

Saratovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. V.I. Razumovskogo Roszdrava, NII fundamental'noĭ i klinicheskoĭ uronefrologii Saratovskogo GMU

Pimenova E.S.

Research Centre of Children’s Health;
I.M. Sechenov First Moscow State Medical University, Moscow

Maslyakova G.N.

V.I. Razumovsky Saratov State Medical University», Saratov

Tsmokaliuk E.N.

Saratovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. V.I. Razumovskogo Roszdrava, NII fundamental'noĭ i klinicheskoĭ uronefrologii Saratovskogo GMU

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