Proliferative activity of the epithelial sheet of the mucous membrane in the lower airways during experimental diabetes mellitus

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Pivovarova O.A.

GU "Luganskiĭ gosudarstvennyĭ meditsinskiĭ universitet", Ukraina

Man'kovskiĭ B.N.

Natsional'naia meditsinskaia akademiia poslediplomnogo obrazovaniia im. P.L. Shupika, Kiev, Ukraina

Proliferative activity of the epithelial sheet of the mucous membrane in the lower airways during experimental diabetes mellitus

Authors:

Pivovarova O.A., Man'kovskiĭ B.N.

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Journal: Problems of Endocrinology. 2013;59(3): 27‑29

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To cite this article:

Pivovarova OA, Man'kovskiĭ BN. Proliferative activity of the epithelial sheet of the mucous membrane in the lower airways during experimental diabetes mellitus. Problems of Endocrinology. 2013;59(3):27‑29. (In Russ.)

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Abstract:

The present study was designed to develop the experimental model of diabetes mellitus based on 5-6 month-old Wistar rats weighing 234.00±2.64 g (n=47). Diabetes was induced by a single intraperitoneal administration of streptozotocin (60 mg/kg, "Sigma", USA) in a 0.1 M citrate buffer solution, pH 4.5. The control group was comprised of 43 intact male rats. The animals with experimental diabetes had a reduced number of secretory cell nuclei per unit area of the epithelial sheet of the bronchial tree; the area of epitheliocyte nuclei also decreased.

Keywords:

experimental diabetes mellitus

epithelial lining

bronchial tree

Authors:

Pivovarova O.A.

GU "Luganskiĭ gosudarstvennyĭ meditsinskiĭ universitet", Ukraina

Man'kovskiĭ B.N.

Natsional'naia meditsinskaia akademiia poslediplomnogo obrazovaniia im. P.L. Shupika, Kiev, Ukraina

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References:

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