Objective. To investigate the regenerative effects of two Russian N-acetyl-6-aminohexanoic acid derivatives in rats with wounds infected with methicillin-resistant Staphylococcus aureus in an experiment. Material and methods. Outbred male and female albino rats weighing 180—220 g were used to simulate postoperative infected and non-infected wounds. The rats were divided into 8 groups of 10 individuals each (5 females and 5 males). The investigation object was calcium (LHT-6-17) and silver (LHT-7-17) salts of N-acetyl-6-aminohexanoic acid as main 1% ointments. Teicoplanin, lyophilisate 200 mg/vial as a main 1% Vaseline ointment, was used as a comparison drug. In Group 1 (a control group), a sterile Vaseline gauze bandage was applied to the wound on the day of surgery; Group 2 received a LHT-6-17-containing liniment; Group 3 used silver (LHT-7-17) salt of N-acetyl-6-aminohexanoic acid, Group 4 had the comparison drug Teicoplanin ointment. 10 µl of methicillin-resistant Staphylococcus aureus was once applied at a concentration of 5´107 ml to a linear wound with a micropipette in Animal Groups 5 to 8 before suturing. The wound was sutured with three interrupted stitches; an ointments gauze bandage was applied to the sutured skin defect as in the first groups. Group 5 was an infection control one. On day 8, the animals were euthanized by ether. In 5 rats from a group, the scar tensile strength was determined with modified dispensing scales, by weighing the increasing mass to the skin flap. Results. Infection of a surgical wound with methicillin-resistant Staphylococcus aureus at a concentration of 5×107 ml led to impaired wound defect healing. A wound healing effect was seen after topical application of calcium (LHT-6-17) and silver (LHT-7-17) salts of N-acetyl-6-aminohexanoic acid as 1% ointment on days 2, 5, and 7 after the simulation of an infected linear wound in rats. The local application of 1% ointments containing the test calcium and silver salts of N-acetyl-6-aminohexanoic acid resulted in a stronger scar than in the control group of both infected and non-infected animals who received placebo as a therapeutic effect. In the control non-infected group of animals, the scar tensile strength averaged 283 g/cm, while contamination with Staphylococcus aureus reduced the scar tensile strength by 2 times. Conclusion. When locally used, LHT-7-17 l accelerates the healing of a linear infected wound of the rat skin by more than twice as in the control, reduces the area of a forming scar defect, by improving its tensile strength.