The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Solovieva E.Yu.

Pirogov Russian National Research Medical University

Small vessels – big problems

Authors:

Solovieva E.Yu.

More about the authors

Journal: Non Nocere. New Therapeutic Journal. 2025;(5‑6): 42‑52

Read: 188 times

Buy for 300₽
Contact the author
Table of contents

To cite this article:

Solovieva EYu. Small vessels – big problems. Non Nocere. New Therapeutic Journal. 2025;(5‑6):42‑52. (In Russ.)

 
ЭндоКард
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Abstract:

Cerebral small vessel disease.

Authors:

Solovieva E.Yu.

Pirogov Russian National Research Medical University

Close metadata

References:

  1. Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol. 2010 Jul;9(7):689-701.  https://doi.org/10.1016/S1474-4422(10)70104-6
  2. Mustapha M, Nassir CMNCM, Aminuddin N, Safri AA, Ghazali MM. Cerebral Small Vessel Disease (CSVD) – Lessons From the Animal Models. Front Physiol. 2019 Oct 24;10:1317. https://doi.org/10.3389/fphys.2019.01317
  3. Wardlaw JM, Smith EE, Biessels GJ, et al. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegen-eration. Lancet Neurol. 2013 Aug;12(8):822-838.  https://doi.org/10.1016/S1474-4422(13)70124-8
  4. Cuadrado-Godia E, Dwivedi P, Sharma S, et al. Cerebral Small Vessel Disease: A Review Focusing on Pathophysiology, Biomarkers, and Machine Learning Strategies. J Stroke. 2018 Sep;20(3):302-320.  https://doi.org/10.5853/jos.2017.02922
  5. Zhang CE, Wong SM, van de Haar HJ, et al. Blood-brain barrier leakage is more widespread in patients with cerebral small vessel disease. Neurology. 2017 Jan 31;88(5):426-432.  https://doi.org/10.1212/WNL.0000000000003556
  6. Huisa BN, Caprihan A, Thompson J, Prestopnik J, Qualls CR, Rosenberg GA. Long-Term Blood-Brain Barrier Permeability Changes in Binswanger Disease. Stroke. 2015 Sep; 46(9):2413-2418. https://doi.org/10.1161/STROKEAHA.115.009589
  7. Inoue Y, Shue F, Bu G, Kanekiyo T. Pathophysiology and probable etiology of cerebral small vessel disease in vascular dementia and Alzheimer’s disease. Mol Neurodegener. 2023 Jul 11;18(1):46.  https://doi.org/10.1186/s13024-023-00640-5
  8. Farrall AJ, Wardlaw JM. Blood-brain barrier: Ageing and microvascular disease – systematic review and meta-analysis. Neurobiol Aging. 2009 Mar;30(3):337-352.  https://doi.org/10.1016/j.neurobiolaging.2007.07.015
  9. Tan R, Traylor M, Rutten-Jacobs L, Markus H. New insights into mechanisms of small vessel disease stroke from genetics. Clin Sci (Lond). 2017 Apr 1;131(7):515-531.  https://doi.org/10.1042/CS20160825
  10. Kalaria RN. The pathology and pathophysiology of vascular dementia. Neuropharmacology. 2018 May 15;134(Pt B):226-239.  https://doi.org/10.1016/j.neuropharm.2017.12.030
  11. Lahna D, Schwartz DL, Woltjer R, et al. Venous Collagenosis as Pathogenesis of White Matter Hyperintensity. Ann Neurol. 2022 Dec;92(6):992-1000. https://doi.org/10.1002/ana.26487
  12. Damulin I.V. Kognitivnye narusheniya pri porazhenii melkikh tserebral’nykh sosudov. Consilium Medicum. 2014. Vol. 16. No. 9. P. 10-16.  https://consilium.orscience.ru/2075-1753/article/view/94119
  13. Levin O.S. Vascular parkinsonism: 20 years later. RMJ. 2017. No. 21. P. 1500–1506.
  14. Schwartz P.G. Phenomenology of neurogenic disorders of urination. RMJ. 2012. No. 18. P. 912. 
  15. Wardlaw JM, Debette S, Jokinen H, et al. ESO Guideline on covert cerebral smallvessel disease. Eur Stroke J. 2021 Jun;6(2):CXI–CLXII. https://doi.org/10.1177/23969873211012132
  16. Goldstein ED, Wolcott Z, Garg G, et al. Effect of Antihypertensives by Class on Cerebral Small Vessel Disease: A Post Hoc Analysis of SPRINT-MIND. Stroke. 2022 Aug;53(8):2435-2440. https://doi.org/10.1161/STROKEAHA.121.037997
  17. Ma Y, Wang M, Chen X, et al. Effect of the Blood Pressure and Antihypertensive Drugs on Cerebral Small Vessel Disease: A Mendelian Randomization Study. Stroke. 2024 Jul;55(7):1838-1846. https://doi.org/10.1161/STROKEAHA.123.045664
  18. Webb AJ, Fischer U, Mehta Z, Rothwell PM. Effects of antihypertensive-drug class on interindividual variation in blood pressure and risk of stroke: a systematic review and meta-analysis. Lancet. 2010 Mar 13;375(9718):906-915.  https://doi.org/10.1016/S0140-6736(10)60235-8
  19. Amarenco P, Bogousslavsky J, Callahan A 3rd, et al. High-dose atorvastatin after stroke or transient ischemic attack. N Engl J Med. 2006 Aug 10;355(6):549-559.  https://doi.org/10.1056/NEJMoa061894
  20. Westover MB, Bianchi MT, Eckman MH, Greenberg SM. Statin use following intracerebral hemorrhage: a decision analysis. Arch Neurol. 2011 May;68(5):573-579.  https://doi.org/10.1001/archneurol.2010.356
  21. Sun Y, Song X, Jin C, Peng Y, Zhou J, Zheng X. Cerebral Small Vessel Disease: Current and Emerging Therapeutic Strategies. Aging Dis. 2025 Feb 17.  https://doi.org/10.14336/AD.2024.1515
  22. Ji T, Zhao Y, Wang J, et al. Effect of Low-Dose Statins and Apolipoprotein E Genotype on Cerebral Small Vessel Disease in Older Hypertensive Patients: A Subgroup Analysis of a Randomized Clinical Trial. J Am Med Dir Assoc. 2018 Nov;19(11):995-1002.e4.  https://doi.org/10.1016/j.jamda.2018.05.025
  23. Bouasquevisque DS, Benavente OR, Shoamanesh A. Antiplatelet Therapy in Cerebral Small Vessel Disease. Curr Neurol Neurosci Rep. 2019 Jul 27;19(9):61.  https://doi.org/10.1007/s11910-019-0979-y
  24. Fakan B, Reisz Z, Zadori D, Vecsei L, Klivenyi P, Szalardy L. Predictors of localization, outcome, and etiology of spontaneous intracerebral hemorrhages: focus on cerebral amyloid angiopathy. J Neural Transm (Vienna). 2020 Jun;127(6):963-972.  https://doi.org/10.1007/s00702-020-02174-2
  25. Choi KH, Kim JH, Lee C, et al. Microbleeds and Outcome in Patients With Acute Ischemic Stroke and Atrial Fibrillation Taking Anticoagulants. Stroke. 2020 Dec;51(12):3514-3522. https://doi.org/10.1161/STROKEAHA.120.030300
  26. Petersen RC, Smith GE, Waring SC, Ivnik RJ, Kokmen E, Tangelos EG. Aging, memory, and mild cognitive impairment. Int Psychogeriatr. 1997;9 Suppl 1:65-69.  https://doi.org/10.1017/s1041610297004717
  27. Kasper S, Bancher C, Eckert A, et al. Management of mild cognitive impairment (MCI): The need for national and international guidelines. World J Biol Psychiatry. 2020 Oct;21(8):579-594.  https://doi.org/10.1080/15622975.2019.1696473
  28. Román GC, Kalaria RN. Vascular determinants of cholinergic deficits in Alzheimer disease and vascular dementia. Neurobiol Aging. 2006 Dec;27(12):1769-1785. https://doi.org/10.1016/j.neurobiolaging.2005.10.004
  29. Peng D; Geriatric Neurology Group, Chinese Society of Geriatrics; Clinical Practice Guideline for Cognitive Impairment of Cerebral Small Vessel Disease Writing Group. Clinical practice guideline for cognitive impairment of cerebral small vessel disease. Aging Med (Milton). 2019 Jun 20;2(2):64-73.  https://doi.org/10.1002/agm2.12073
  30. Battle CE, Abdul-Rahim AH, Shenkin SD, Hewitt J, Quinn TJ. Cholinesterase inhibitors for vascular dementia and other vascular cognitive impairments: a network meta-analysis. Cochrane Database Syst Rev. 2021 Feb 22;2(2):CD013306. https://doi.org/10.1002/14651858.CD013306.pub2
  31. McShane R, Westby MJ, Roberts E, et al. Memantine for dementia. Cochrane Database Syst Rev. 2019 Mar 20;3(3):CD003154. https://doi.org/10.1002/14651858.CD003154.pub6
  32. Wei W, Ma D, Li L, Zhang L. Cognitive impairment in cerebral small vessel disease induced by hypertension. Neural Regen Res. 2024 Jul 1;19(7):1454-1462. https://doi.org/10.4103/1673-5374.385841
  33. Salvadori E, Poggesi A, Donnini I, et al. Association of nimodipine and choline alphoscerate in the treatment of cognitive impairment in patients with cerebral small vessel disease: study protocol for a randomized placebo-controlled trial-the CONIVaD trial. Aging Clin Exp Res. 2020 Mar;32(3):449-457.  https://doi.org/10.1007/s40520-019-01229-z
  34. Gavrilova SI, Preuss UW, Wong JW, et al. Efficacy and safety of Ginkgo biloba extract EGb 761 in mild cognitive impairment with neuropsychiatric symptoms: a randomized, placebo-controlled, double-blind, multi-center trial. Int J Geriatr Psychiatry. 2014 Oct;29(10):1087-1095. https://doi.org/10.1002/gps.4103
  35. Frederiksen KS, Verdelho A, Madureira S, et al. Physical activity in the elderly is associated with improved executive function and processing speed: the LADIS Study. Int J Geriatr Psychiatry. 2015 Jul;30(7):744-750.  https://doi.org/10.1002/gps.4220
  36. Wong A, Mak MKY, Lam LCW, Mok VCT. Aerobic dance for cognitive and physical functions and mood in older adults with cerebral small vessel disease: abridged secondary publication. Hong Kong Med J. 2020 Dec;26 Suppl 6(6):38-41. 
  37. Gons RA, van Norden AG, de Laat KF, et al. Cigarette smoking is associated with reduced microstructural integrity of cerebral white matter. Brain. 2011 Jul;134(Pt 7):2116-2124. https://doi.org/10.1093/brain/awr145
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.