The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Piketty M.-L.

Service des explorations fonctionnelles, G.H. Necker Enfants Malades, Paris, France

Polak M.

Service d’ endocrinologie, gynécologie et diabétologie pédiatriques, G.H. Necker Enfants Malades, Paris, France

Flechtner I.

Service d’ endocrinologie, gynécologie et diabétologie pédiatriques, G.H. Necker Enfants Malades, Paris, France

Gonzales-Briceno L.

Service d’ endocrinologie, gynécologie et diabétologie pédiatriques, G.H. Necker Enfants Malades, Paris, France

Souberbielle J.-C.

Service d’ endocrinologie, gynécologie et diabétologie pédiatriques, G.H. Necker Enfants Malades, Paris, France

False biochemical diagnosis of hyperthyroidism in streptavidin-biotin-based immunoassays: the problem of biotin intake and related interferences

Authors:

Piketty M.-L., Polak M., Flechtner I., Gonzales-Briceno L., Souberbielle J.-C.

More about the authors

Journal: Laboratory Service. 2018;7(4): 48‑57

DOI: 10.17116/labs2018704148

Read: 9125 times

Download PDF (RU)
Contact the author
Table of contents

FALSE BIOCHEMICAL DIAGNOSIS OF HYPERTHYROIDISM IN STREPTAVIDIN-BIOTIN-BASED IMMUNOASSAYS: THE PROBLEM OF BIOTIN INTAKE AND RELATED INTERFERENCES
FALSE BIOCHEMICAL DIAGNOSIS OF HYPERTHYROIDISM IN STREPTAVIDIN-BIOTIN-BASED IMMUNOASSAYS: THE PROBLEM OF BIOTIN INTAKE AND RELATED INTERFERENCES

To cite this article:

Piketty M-L, Polak M, Flechtner I, Gonzales-Briceno L, Souberbielle J-C. False biochemical diagnosis of hyperthyroidism in streptavidin-biotin-based immunoassays: the problem of biotin intake and related interferences. Laboratory Service. 2018;7(4):48‑57. (In Russ.)
https://doi.org/10.17116/labs2018704148

Подписка 2025 Лабораторная служба (Laboratory Service)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Abstract:

Keywords:

anti-streptavidin antibody; biotin; immunoassay; interference

Authors:

Piketty M.-L.

Service des explorations fonctionnelles, G.H. Necker Enfants Malades, Paris, France

Polak M.

Service d’ endocrinologie, gynécologie et diabétologie pédiatriques, G.H. Necker Enfants Malades, Paris, France

Flechtner I.

Service d’ endocrinologie, gynécologie et diabétologie pédiatriques, G.H. Necker Enfants Malades, Paris, France

Gonzales-Briceno L.

Service d’ endocrinologie, gynécologie et diabétologie pédiatriques, G.H. Necker Enfants Malades, Paris, France

Souberbielle J.-C.

Service d’ endocrinologie, gynécologie et diabétologie pédiatriques, G.H. Necker Enfants Malades, Paris, France

Close metadata

References:

  1. Decoudier B, Delemer B, Maarouf A, Tourbah A, Marot D. Une hyperthyroïdie énigmatique de l’importance des interférences dans les dosages hormonaux. 32e SFE congress. oct 2015, Poster P172. Annales d’ Endocrinologie. 2015;76(4):428. https://doi.org/10.1016/j.ando.2015.07.419
  2. Barbesino G. Misdiagnosis of Graves’ disease with apparent severe hyperthyroidism in a patient taking biotin megadoses. Thyroid. 2016;26(6):860-863. https://doi.org/10.1089/thy.2015.0664
  3. Elston M, Sehgal S, Du Toit S, Yarndley T, Conaglen JV. Facticious Graves’ disease due to biotin immunoassay interference — a case and review of the literature. The Journal of Clinical Endocrinology & Metabolism. 2016;101(9):3251-3255. https://doi.org/10.1210/jc.2016-1971
  4. Khieng V, Stevens C. Vitamin D toxicity? A case study. NZ J Med Lab Sci. 2010;64:44-50.
  5. Meany D, J De Beur S, Bill M, Sokoll L. A case of renal osteodystrophy with unexpected serum intact parathyroid hormone concentrations. Clinical Chemistry. 2009;55(9):1737-1741. https://doi.org/10.1373/clinchem.2008.121921
  6. Simó-Guerrero O, Giménez-Pérez G, Recsens-Garci A, Villà- Blasco C, Castells-Fusté I. False overt hyperthyroidism by interference in immunoassays. Endocrinología y Nutrición. 2016;63(8):431-432. https://doi.org/10.1016/j.endoen.2016.09.010
  7. Waghray A, Milas M, Nyalakonda K, Siperstein A. Falsely low parathyroid hormone secondary to biotin interference: a case series. Endocrine Practice. 2013;19(3):451-455. https://doi.org/10.4158/EP12158.OR
  8. Seaborg E. Thyroid month January 2016: beware of biotin. In endocrine news. Washington, USA. Endocrine society. 2016;42. Available at: http://endocrinenews.endocrine.org/January-2016-thyroid-month-beware-of-biotin
  9. National Research Council. Dietary reference intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic acid, Biotin, and Choline. National Academy of Sciences. Washington, DC: National Academy press; 1998:374-389. https://doi.org/10.17226/6015
  10. Zempleni J, Wijeratne S, Hassan Y. Biotin. Biofactors. 2009;35:36-46. https://doi.org/10.1002/biof.8
  11. Kwok JS, Chan IH, Chan MH. Biotin interference on TSH and free thyroid hormone measurement. Pathology. 2012;44:278-280. https://doi.org/10.1097/PAT.0b013e3283514002
  12. Henry J, Sobki S, Arafat N. Interference by biotin therapy on measurement of TSH and FT4 by enzymeimmunoassay on Boehringer Mannheim ES700 analyser. Annals of Clinical Biochemistry. 1996;33(2):162-163. https://doi.org/10.1177/000456329603300214
  13. Wijeratne N, Doery J, Lu Z. Positive and negative interference in immunoassays following biotin ingestion: a pharmacokinetic study. Pathology. 2012;44:674-675. https://doi.org/10.1097/PAT.0b013e32835a3c17
  14. Sedel F, Papeix C, Bellanger A, Touitou V, Lebrun-Frenay C, Galanaud D, et al. High doses of biotin in chronic progres- sive multiple sclerosis: a pilot study. Mult Scler relat Disord. 2015;4:159-169. https://doi.org/10.1016/j.msard.2015.01.005
  15. Saint PL, Debruyne D, Bernard D, Mock D, Defer G. Pharmacokinetics and pharmacodynamics of MD1003 (high dose biotin) in the treatment of progressive multiple sclerosis. Expert Opin Drug Metab Toxicol. 2016;12:327-344. https://doi.org/10.1517/17425255.2016.1136288
  16. Rulander N, Cardamome D, Senior M, Snyder P, Master S. Interference from anti-streptavidin antibody. Arch Pathol Lab Med. 2013;137:1141-1146. https://doi.org/10.5858/arpa.2012-0270-CR
  17. Peltier L, Massart C, Moineau MP, Delhostal A, Roudaut N. Anti-streptavidin interferences in Roche Thyroid immunoassays: a case report [letter]. Clin Chem Lab Med. 2016;54:e11-e14. https://doi.org/10.1515/cclm-2015-0350
  18. Selby C. Interference in immunoassay. Ann Clin Biochem 1999;36:704-721. https://doi.org/10.1177/000456329903600603
  19. Tate J, Ward G. Interferences in immunoassay. Clin Biochem Rev. 2004;25(2):105-119. PMC1904417
  20. Gulbahar O, Degertekin C, Akturk M, Yalcin M, Kalan I, AtikeÂler G. A case with immunoassay interferences in the measurement of multiple hormones. J Clin Endocrinol Metab. 2015;100:2147-2153. https://doi.org/10.1210/jc.2014-4023
  21. Mongolu S, Armston AE, Mozley E, Nasruddin A. HeteroÂphilic antibody interference affecting multiple hormone assays: is it due to rheumatoid factor? Scand J Clin Lab Invest. 2016;76:240-242. https://doi.org/10.3109/00365513.2016.1143113
  22. Faix JD. Principles and pitfalls of free hormone measurements. Best Pract Res Clin Endocrinol Metab 2013;27:631-645. https://doi.org/10.1016/j.beem.2013.06.007
  23. Ohba K, Noh JY, Unno T, Satoh T, Iwahara K, Matsushita A. Falsely elevated thyroid hormone levels caused by anti-ruthenium interference in the Elecsys assay resembling the syndrome of inappropriate secretion of thyrotropin. Endocr J. 2012;59(8):663-667. PMID: 22673200
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.