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Kostyleva O.I.
N.N. Blokhin Russian Cancer Research Center, Moscow, Russia
Mushtenko V.V.
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov, Moscow, Russia
Kolpakov A.V.
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov, Moscow, Russia
Timofeev Y.S.
N.N. Blokhin Russian Cancer Research Center, Moscow, Russia
Kushlinskiĭ N.E.
Rossiĭskiĭ onkologicheskiĭ nauchnyĭ tsentr im. N.N. Blokhina RAMN, Moskva
Features of expression matrix metalloproteinases, their tissue inhibitors and renal cancer
Journal: Laboratory Service. 2017;6(1): 6‑13
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To cite this article:
Kostyleva OI, Mushtenko VV, Kolpakov AV, Timofeev YS, Kushlinskiĭ NE. Features of expression matrix metalloproteinases, their tissue inhibitors and renal cancer. Laboratory Service.
2017;6(1):6‑13. (In Russ.)
https://doi.org/10.17116/labs2017616-13
A review of the literature is devoted to the role of the system of matrix metalloproteinases and their tissue inhibitors in renal carcinoma. Due to the absence of screening, diagnostic models for early diagnosis, as well as specific monitoring of relapse for renal tumors, the urgent task is the identification of new biomarkers of renal tumor. Recent studies demonstrate the prospects of using the system MMP/TIMP not only as a diagnostic but also a prognostic marker in some renal tumors, as well as to assess the effectiveness of targeting anticancer therapy.
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Authors:
Kostyleva O.I.
N.N. Blokhin Russian Cancer Research Center, Moscow, Russia
Mushtenko V.V.
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov, Moscow, Russia
Kolpakov A.V.
Moscow State University of Medicine and Dentistry named after A.I. Evdokimov, Moscow, Russia
Timofeev Y.S.
N.N. Blokhin Russian Cancer Research Center, Moscow, Russia
Kushlinskiĭ N.E.
Rossiĭskiĭ onkologicheskiĭ nauchnyĭ tsentr im. N.N. Blokhina RAMN, Moskva
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