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Likhonos L.M.

FGBOU VO «Sankt-Peterburgskij gosudarstvennyj universitet», Sankt-Peterburg, Rossija, 199034

Smirnova I.O.

Sankt-Peterburgskiĭ gosudarstvennyĭ universitet, Sankt-Peterburg, Rossiia, 199106

Pustulosis palmaris et plantaris: pathogenetic, clinical, and epidemiological features

Authors:

Likhonos L.M., Smirnova I.O.

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Journal: Russian Journal of Clinical Dermatology and Venereology. 2017;16(3): 4‑12

DOI: 10.17116/klinderma20171634-12

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To cite this article:

Likhonos LM, Smirnova IO. Pustulosis palmaris et plantaris: pathogenetic, clinical, and epidemiological features. Russian Journal of Clinical Dermatology and Venereology. 2017;16(3):4‑12. (In Russ.)
https://doi.org/10.17116/klinderma20171634-12

 
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Pustulosis palmaris et plantaris is a rare chronic dermatosis characterized by formation of sterile pustules on the skin of palms and soles and torpid, relapsing course. Disease occurs mainly in middle-aged females and is strongly associated with smoking. Some authors consider pustulosis palmaris et plantaris as independent disease, while other still consider it as a form of psoriasis, using the previous term «Barber’s pustular psoriasis». The lack of consensus in the terminology and classification reflects ambiguity in pathogenesis of this dermatosis. When considering pustulosis in the context of psoriatic lesions, it is still unclear, why autoinflammatory response dominate over autoimmune. At the same time, the discovery of the role of mutations of IL-36(IL36RA) receptor antagonist gene in the development of some forms of generalized pustular psoriasis and Hallopeau acrodermatitis allowed some authors to refer pustulosis palmaris et plantaris as an autoinflammatory pustular neutrophilic dermatose. In this review, we collected and analyzed epidemiological, pathogenetic, and clinical data of different population studies of patients with palmoplantar pustulosis published in the recent literature.

Keywords:

pustulosis palmaris et plantaris
palmoplantar pustulosis
pustular psoriasis of palms and soles

Authors:

Likhonos L.M.

FGBOU VO «Sankt-Peterburgskij gosudarstvennyj universitet», Sankt-Peterburg, Rossija, 199034

Smirnova I.O.

Sankt-Peterburgskiĭ gosudarstvennyĭ universitet, Sankt-Peterburg, Rossiia, 199106

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