The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Kasikhina E.I.

State Educational Institution of additional professional education "Russian Academy of Continuous Medical Education"

Kolbina M.S.

State Institute of Advanced Medical Training, Ministry of Defense of the Russian Federation

The use of retinol to correct age-related skin changes: a review of clinical effectiveness and safety

Authors:

Kasikhina E.I., Kolbina M.S.

More about the authors

Journal: Russian Journal of Clinical Dermatology and Venereology. 2014;12(6): 115‑119

Views: 12061

Downloaded: 304

Download PDF (RU)
Contact the author
Table of contents

To cite this article:

Kasikhina EI, Kolbina MS. The use of retinol to correct age-related skin changes: a review of clinical effectiveness and safety. Russian Journal of Clinical Dermatology and Venereology. 2014;12(6):115‑119. (In Russ.)

 
МСФ на ЯМ
Close metadata
Recommended articles:
Non-invasive hardware methods of skin condition diagnosis. Russian Journal of Clinical Dermatology and Vene­reology. 2024;(3):332-338

The paper focuses on biological features of skin aging and possibilities of using retinol in clinical practice. The data on safety and effectiveness of Russian dermatoprotecting agent redecil are reported.

Keywords:

retinol
retinol
Redecil
Redecil
skin aging
skin aging

Authors:

Kasikhina E.I.

State Educational Institution of additional professional education "Russian Academy of Continuous Medical Education"

Kolbina M.S.

State Institute of Advanced Medical Training, Ministry of Defense of the Russian Federation

List of references:

  1. Guinot C., Malvy D.J., Ambroisine L. et al. Relative Contribution of Intrinsic vs Extrinsic Factors to Skin Aging as Determined by a Validated Skin Age Score. Arch Dermatol 2002; 138: 1454-1460.
  2. Baumann L. Skin ageing and its treatment. J Pathol 2007; 211: 241-251.
  3. Waller J.M., Maibach H.I. Age and skin structure and function, a quantitative approach (II): protein, glycosaminoglycan, water, and lipid content and structure. Skin Res Technol 2006; 12: 145-154.
  4. Castle S.C. Clinical relevance of age-related immune dysfunction. Clin Infect Dis 2000; 31: 578-585.
  5. Darlenski R., Surber C., Fluhr J.W. Topical retinoids in the management of photodamaged skin: from theory to evidence-based practical approach. Br J Dermatol 2010; 163: 6: 1157-1165.
  6. Baumann L., Vujevich J., Halem M., Martin L.K. еt al. Open-label pilot study of alitretinoin gel 0.1% in the treatment of photoaging. Cutis 2005; 76: 1: 69-73.
  7. Ramos-e-Silva M., Celem L.R., Ramos-e-Silva S., Fucci-da-Costa A.P. Anti-aging cosmetics: facts and controversies. Clin Dermatol 2013; 31: 6: 750-758.
  8. Mukherjee S., Date A., Patravale V., Korting H.C. et al. Retinoids in the treatment of skin aging: an overview of clinical efficacy and safety. Clin Interv Aging 2006; 1: 4: 327-348.
  9. Rolewski S.L. Clinical review: topical retinoids. Dermatol Nurs 2003; 15: 5: 447-450, 459-465.
  10. Kafi R., Kwak H.S., Schumacher W.E. et al. Improvement of naturally aged skin with vitamin A (retinol). Arch Dermatol 2007; 143: 606-609.
  11. Rawlings A.V., Stephens T.J., Herndon J.H., Miller M. The effect of a vitamin A palmitate and antioxidant-containing oil-based moisturizer on photodamaged skin of several body sites. J Cosmet Dermatol 2013; 12: 1: 25-35.
  12. Бауманн Л. Косметическая дерматология. Принципы и практика. Пер. с англ. Под ред. Н.Н. Потекаева. М 2012.
  13. Uma Shankar Agarwal, Raj Kumar Besarwal, Rahul Gupta. Hand Eczema. Indian J Dermatol 2014; 59: 3: 213-224.
  14. Afornali A., de Vecchi R., Stuart R.M. Triple nanoemulsion potentiates the effects of topical treatments with microencapsulated retinol and modulates biological processes related to skin aging. An Bras Dermatol 2013; 88: 6: 930-936.
  15. Maggini S., Wintergerst E.S., Beveridge S. et al. Selected vitamins and trace elements support immune function by strengthening epithelial barriers and cellular and humoral immune responses. Br J Nutr 2007; 98: 29.
  16. Seité S., Bredoux C., Compan D. et al. Histological evaluation of a topically applied retinol-vitamin C combination. Skin Pharmacol Physiol 2005; 18: 2: 81-87.
  17. Fluhr J.W., Vienne M.P., Lauze C. et al. Tolerance profile of retinol, retinaldehyde and retinoic acid under maximized and long-term clinical conditions. Dermatology 1999; 199: 1: 57-60.
  18. Kang S., Duell E.A., Fisher G.J. et al. Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. J Invest Dermatol 1995; 105: 4: 549-556.
  19. Darlenski R., Surber C., Fluhr J.W. Topical retinoids in the management of photodamaged skin: from theory to evidence-based practical approach. Br J Dermatol 2010; 163: 6: 1157-1165.
  20. Baumann L., Vujevich J., Halem M., Martin L.K. еt al. Open-label pilot study of alitretinoin gel 0.1% in the treatment of photoaging. Cutis 2005; 76: 1: 69-73.
  21. Fisher G.J., Datta S.C., Talwar H.S. et al. Molecular basis of sun-induced premature skin ageing and retinoid antagonism. Nature 1996; 379: 355-359.
  22. Liu P.T., Krutzik S.R., Kim J. et al. Cuttng edge: all-trans retinoic acid down-regulates TLR2 expression and function. J Immunol 2005; 174: 2467-2470.
  23. Varani J., Warner R.L., Gharaee-Kermani M. et al. Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin. J Invest Dermatol 2000; 114: 3: 480-486.
  24. Spring P., Bigliardi P. Chronic hand eczema, conventional and new treatments. Rev Med Suisse 2012; 8: 335: 736-738, 740-742.
  25. Paulden M., Rodgers M., Griffin S. et al. Alitretinoin for the treatment of severe chronic hand eczema. Health Technol Ass 2010; 14: Suppl 1: 39-46.
  26. Lahfa M. Management of chronic hand eczema. Ann Dermatol Venereol 2014; 141: Suppl 1: S143-S150.
  27. Альбанова В.И., Петрова С.Ю. Клиническая эффективность препарата Редецил при атопическом дерматите. Научно-практическая конференция "Актуальные вопросы терапии инфекций, передаваемых половым путем, и хронических дерматозов": Тезисы. Екатеринбург 2002.
  28. Альбанова В.И. Наружное лечение атопического дерматита. Врач 2006; 2: 76-78.
  29. Яцковский А.Н., Белоусова Т.А., Архапчев Ю.П., Кинзирский А.С., Лаврик О.И., Жучков С.А., Ноздрин В.И. Влияние препарата Редецил на процессы репаративной регенерации кожи. Национальный конгресс "Человек и лекарство", 8-й: Тезисы. М 2001.
  30. Shirakata Y., Kimura R., Nanba D. еt al. Heparin-binding EGF-like growth factor accelerates keratinocyte migration and skin wound healing. J Cell Sci 2005; 118: 11: 2363-2370.
  31. Ноздрин В.И., Белоусова Т.А., Жучков С.А., Крутых Е.Г. Иммуноморфологические подходы к изучению действия ретиноидов на эпидермис. В сб.: Ретиноиды. М 2005.
  32. Саницкий В.Б., Альбанова В.И. Препарат Редецил в практике хирурга. Бабухинские чтения в Орле. Всероссийская научная конференция, 8-я: Материалы. М 2011.
  33. Оценка клинической эффективности, переносимости и безопасности мази Редецил в комплексном лечении заболеваний хирургического профиля.
  34. Яцковский А.Н., Белоусова Т.А., Кинзирский А.С., Ноздрин В.И. Исследование хронической токсичности препарата Редецил. I Национальный конгресс "Человек и лекарство", 8-й: Тезисы. М 2001.
  35. Ноздрин В.И., Лаврик О.И., Бобылев В.П., Гузев К.С. Исследование возможного местно-раздражающего и аллергизирующего действия препарата Редецил. Национальный конгресс "Человек и лекарство", 8-й: Тезисы. М 2001.
  36. Hubbard B.A., Unger J.G., Rohrich R.J. Reversal of skin aging with topical retinoids. Plast Reconstr Surg 2014; 133: 4: 481-490.

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.