Granulocytes function in patients with chronic venous insufficiency followed by chronic wounds

Vinnik Yu.S.

Krasnoyarsk State Medical University. prof. V.F Voyno-Yasenetsky, Krasnoyarsk, Russia;
Clinical Hospital №7, Krasnoyarsk, Russia

Karapetyan G.E.

Voyno-Yasenetsky Krasnoyarsk State Medical University of Healthcare Ministry of the Russia, Krasnoyarsk, Russia

Kochetova L.V.

V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University of Healthcare Ministry of the Russian Federation

Pakhomova R.A.

V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University of Healthcare Ministry of the Russian Federation

Granulocytes function in patients with chronic venous insufficiency followed by chronic wounds

Authors:

Vinnik Yu.S., Karapetyan G.E., Kochetova L.V., Pakhomova R.A.

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Journal: Pirogov Russian Journal of Surgery. 2019;(1): 37‑42

DOI: 10.17116/hirurgia201901137

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To cite this article:

Vinnik YuS, Karapetyan GE, Karapetyan GE, Kochetova LV, Pakhomova RA. Granulocytes function in patients with chronic venous insufficiency followed by chronic wounds. Pirogov Russian Journal of Surgery. 2019;(1):37‑42. (In Russ.)
https://doi.org/10.17116/hirurgia201901137

Подписка 2025 (Pirogov Russian Journal of Surgery)

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Aim — to analyze efficiency of ozone therapy, ultrasound and cryotherapy for infected and purulent wounds due to chronic venous insufficiency. Material and methods. There were 127 patients with chronic venous insufficiency followed by chronic wounds. Efficacy of systemic and local ozone therapy was assessed. De Sole method was used to analyze chemiluminescent and spontaneous activity of neutrophils of peripheral blood. Results. Advanced generation of active forms of oxygen was revealed in patients with chronic wounds and chronic venous insufficiency. Complex ozone therapy including intravenous administration of ozonized autologous blood, oxygen-ozone and ultrasonic exposure of the wound and cryogenic stimulation reduce painful period up to 3.1±0.6 days, accelerate epithelialization of the wound and normalize release of active forms of oxygen.

Keywords:

chronic wounds

ozone

chemiluminescence of neutrophils

complex treatment

Authors:

Vinnik Yu.S.

Krasnoyarsk State Medical University. prof. V.F Voyno-Yasenetsky, Krasnoyarsk, Russia;
Clinical Hospital №7, Krasnoyarsk, Russia

Karapetyan G.E.

Voyno-Yasenetsky Krasnoyarsk State Medical University of Healthcare Ministry of the Russia, Krasnoyarsk, Russia

Kochetova L.V.

V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University of Healthcare Ministry of the Russian Federation

Pakhomova R.A.

V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University of Healthcare Ministry of the Russian Federation

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