The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 101-59-87
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Skripko V.D.

GVUZ "Ivano-Frankovskiĭ natsional'nyĭ meditsinskiĭ universitet"

Kovalenko A.L.

Direktsiia po nauke OOO "NTFF "Polisan", Sankt-Peterburg

Zaplutanov V.A.

I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, Saint Petersburg, Russia

Effect of the Cytoflavin on the distal polyneuropathy severity in patients with diabetic foot syndrome with arteries mediacalcinosis

Authors:

Skripko V.D., Kovalenko A.L., Zaplutanov V.A.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2017;(8): 75‑78

DOI: 10.17116/hirurgia2017875-78

Views: 1902

Downloaded: 27

Download PDF (RU)
Contact the author
Table of contents

To cite this article:

Skripko VD, Kovalenko AL, Zaplutanov VA. Effect of the Cytoflavin on the distal polyneuropathy severity in patients with diabetic foot syndrome with arteries mediacalcinosis. Pirogov Russian Journal of Surgery. 2017;(8):75‑78. (In Russ.)
https://doi.org/10.17116/hirurgia2017875-78

Подписка 2025 (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
Close metadata
Recommended articles:
Role and place of ipidacrine in the therapy of diseases of the peri­pheral nervous system. The reso­lution of the expert council. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(2):158-164
Factors of the hemo­stasis system as biomarkers of severe course of acute viral infe­ctions. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(3):63-74
B vita­mins and diseases of the peri­pheral nervous system. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(5):75-82
Clinical and diagnostic inve­stigation of neopterin level in complication of leprosy. Russian Journal of Clinical Dermatology and Vene­reology. 2024;(4):392-397
Severe traumatic brain injury with damage to the posterior cranial fossa in a teenager. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(8):113-117
Neuroprotective effect of cyto­flavin in the treatment of premature newborns with hypo­xic-ischemic ence­phalopathy. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(9):68-72
Improving the effe­ctiveness of treatment of patients with post-stroke apha­sia. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(10):22-28
Diagnosis of neuroinfections in children. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(11-2):51-59
The role of drug Cyto­flavin in the correction of dysautonomia in patients with post-COVID syndrome. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(11):140-146
Main dire­ctions in corneal nerve fibers research. Russian Annals of Ophthalmology. 2024;(6):118-124

The aim of the study was to evaluate the effectiveness of cytoflavin in the complex treatment of patients with diabetic foot syndrome. Material and methods. The research is based on the results of a comprehensive survey of 140 people with diabetic foot syndrome. Depending on the treatment, all patients were divided into 2 groups. The first group (n=35) received basic therapy. The second group (n=35) in addition to basic therapy received cytoflavin 10 ml (+200 ml 0.9% NaCl) for 10 days, followed by switching to the tablet form of the drug 2 tablets twice a day for 1 month. Results. Analyzing the severity of polyneuropathy after treatment, we noted a more positive dynamic in patients who in addition to standard therapy received cytoflavin.

Keywords:

diabetic foot syndrome
mediacalcification
polyneuropathy
cytoflavin

Authors:

Skripko V.D.

GVUZ "Ivano-Frankovskiĭ natsional'nyĭ meditsinskiĭ universitet"

Kovalenko A.L.

Direktsiia po nauke OOO "NTFF "Polisan", Sankt-Peterburg

Zaplutanov V.A.

I.M. Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, Saint Petersburg, Russia

List of references:

  1. Bensman VM, Triandafilov KG. Discussion questions of the classification of diabetic foot syndrome. Hirurgija. 2009;4:37-41. (In Russ.).
  2. Grekova NM, Bordunovskij VN, Gur’eva IV. Diagnostika i hirurgicheskoe lechenie sindroma diabeticheskoj stopy. Chelyabinsk: Publishing house PIRS; 2010. (In Russ.).
  3. Udovichenko OV, Grekova NM. Diabeticheskaja stopa. M. Prakticheskaja medicina; 2010. (In Russ.).
  4. Атаман Ю.О. Дослідження особливостей ураження артерій нижніх кінцівок у людей старечого віку, хворих на цукровий діабет 2 типу. Вісник СумДУ. Серія Медицина. 2009;1:47-49. [Ataman YuO. Studies of lesions of arteries of the lower extremities in elderly people suffering from type 2 diabetes. Vestnik SumDU. Serija Medicina. 2009;1:47-49. (In Ukrainian).
  5. Markevich YuO, Bojko NІ, Pavlovs’kij MP. Modern approach to classification, diagnosis and treatment of complex diabetic foot. AМL ХІ. 2005;4:105-109. (In Ukrainian).
  6. Forst T, Kann P, Lobmann R. Association between diabetic-autonomic neuropathy and medial wall calcification in the outcome of trophic foot lesion. Exp Clin Endocrinol Diabetes. 2005;2:94-98.
  7. Edmonds M, Morrison N, Laws J. Medial arterial calcification and diabetic neuropathy. Br Med J. 2009;284:928-930.
  8. Goebel F, Fussel H. Monckeberg’s sclerosis after sympathetic denervation in diabetic and non-diabetic subjects. Diabetologia. 2003;24:347-350.
  9. Mayfield J, Caps М, Boyko Е. Relationship of medial arterial calcinosis to autonomic neuropathy and adverse outcomes in a diabetic veteran population. J Diabetes Complications. 2002;16(2):165-171.
  10. Markevich PS, Markevich LB, Danilenko SYu, Plehanov AN. Experience of application of preparation cytoflavin in patients with the syndrome of diabetic foot. Bjulleten’ VSNC SO RAMN. 2013;2(2):44-49. (In Russ.).
  11. Markevich PS, Danilenko SYu, Jankin AV. The priority directions of use of Cytoflavin. Bjulleten’ VSNC SO RAMN. 2010;3:109-112. (In Russ.).

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register


We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.