Results of the examination of patients with secondary lymphedema in the period 2006-2010. Revealed that the most frequent concomitant diseases in 150 (57,6%) patients with secondary lymphostasis lower extremities is hyperthyroidism. Clinical manifestations: an increase in thyroid size, infiltrative endocrine ophthalmopathy; balanced, solid consistency swelling of the lower extremities to the level of the upper third of the leg; hyperkeratosis; paresthesias. The results of functional studies of the condition of peripheral lymph in patients with different stages of secondary lymphostasis lower extremities against a background of hyperthyroidism showed a direct relationship between the severity of the disease, the degree of decompensation of peripheral lymph and the state of thyroid function.