Use of the prokinetic domperidine in patients in the early postoperative period

Alekseeva E.V.

Tsentral'naia klinicheskaia bol'nitsa s poliklinikoĭ UD Prezidenta RF, Moskva

Fominykh V.P.

Tsentral'naia klinicheskaia bol'nitsa s poliklinikoĭ UD Prezidenta RF, Moskva

Tropskaia N.S.

NII skoroĭ pomoshchi im. N.V. Sklifosovskogo, Moskva

Popova T.S.

NII skoroĭ pomoshchi im. N.V. Sklifosovskogo, Moskva

Use of the prokinetic domperidine in patients in the early postoperative period

Authors:

Alekseeva E.V., Fominykh V.P., Tropskaia N.S., Popova T.S.

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Journal: Pirogov Russian Journal of Surgery. 2010;(3): 62‑69

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To cite this article:

Alekseeva EV, Fominykh VP, Tropskaia NS, Popova TS. Use of the prokinetic domperidine in patients in the early postoperative period. Pirogov Russian Journal of Surgery. 2010;(3):62‑69. (In Russ.)

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The work focuses on the comparison of influence of domperidone and metoclopramide on rehabilitation of motor-evacuation function of stomach and small intestine in 82 patients with post-surgical flatulent distention. For group 1 (n=50) - metoclopramide was administered intravenously from the 1st postoperative day, 10 mg 3 times a day. For group 2 (n=32) - domperidone was used from the 1st postoperative day (motilium suspension), 20 ml 4 times a day. The results of gastrointestinal tract capacity rehabilitation were evaluated using the data of peripheral electrogastroenterography, enteral balance, a complex of radial diagnostics methods. Application of domperidone in patients with post-surgical flatulent distention resulted in quicker gastrointestinal tract motor resolution.

Keywords:

domperidone

metoclopramide

flatulent distention

intensive care unit patients

peripheral electrogastroenterography

Authors:

Alekseeva E.V.

Tsentral'naia klinicheskaia bol'nitsa s poliklinikoĭ UD Prezidenta RF, Moskva

Fominykh V.P.

Tsentral'naia klinicheskaia bol'nitsa s poliklinikoĭ UD Prezidenta RF, Moskva

Tropskaia N.S.

NII skoroĭ pomoshchi im. N.V. Sklifosovskogo, Moskva

Popova T.S.

NII skoroĭ pomoshchi im. N.V. Sklifosovskogo, Moskva

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