Objective — to comparative in-hospital results of endovasal laser obliteration (EVLO) and combined phlebectomy (CF) in patients with lower limb varicose vein disease. Material and methods. There were 408 patients with lower limb varicose vein disease who were divided into two groups depending on the treatment strategy. Group 1 — endovasal laser obliteration (n=257, 63%), group 2 — combined phlebectomy (n=151, 37%). CF was performed in standard fashion. Laser with a wavelength of 1470 nm was used for EVLO. The results of treatment were evaluated in 7 days after intervention. Results. Both groups were comparable by the absolute majority of all clinical and instrumental characteristics. CEAP grades and VCSS scores were also similar. According to the ultrasound, recanalization was absent in both groups on the 7th day after surgery. EVLO was characterized by less rehabilitation period, need for non-steroidal anti-inflammatory drugs. As a result, higher VCSS score was observed in CF group. Conclusion. Both treatment strategies were characterized by the same effectiveness by the 7th day after intervention. Lower VCSS score, less pain syndrome and rehabilitation period were observed after EVLO.