Unfavorable prognostic factors in patients with atrial fibrillation after successful transcatheter aortic valve implantation

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OBJECTIVE

To assess all-cause mortality and identify unfavorable clinical prognostic factors.

MATERIAL AND METHODS

We analyzed 130 patients (61 men, median age 79 years) with atrial fibrillation who underwent transcatheter aortic valve implantation at the National Medical Research Center of Cardiology between 2020 and 2022. Most patients had high risk of thromboembolic complications (median CHA₂DS₂-VASc score 5).

RESULTS

Mortality within 1.5 years after successful transcatheter aortic valve implantation was 8.4/100 patient-years. Cardiovascular mortality prevailed (73.3%). Predictors of all-cause mortality were senile asthenia and chronic kidney disease stage ≥3. In patients with atrial fibrillation who survived transcatheter aortic valve implantation, the predictor of all adverse events throughout 1.5-year follow-up was cancer.

Keywords:

atrial fibrillation

anticoagulation

transcatheter aortic valve implantation

fragility

frailty

chronic kidney disease

poor prognosis

all-cause mortality

Authors:

Staroverova A.I.

Chazov National Medical Research Center of Cardiology

Kropacheva E.S.

National Medical Research Center of Cardiology

Panchenko E.P.

National Medical Research Center of Cardiology

Komlev A.E.

Chazov National Research Center of Cardiology

ORCID: 0000-0001-6908-7472

Imaev T.E.

Chazov National Research Center of Cardiology

ORCID: 0000-0002-5736-5698

Received:

04.09.2022

Accepted:

09.09.2022

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