Purpose — improvement of the results of palliative internal choleresis in patients with tumor mechanical jaundice. Material and methods. Decompression of the bile ducts by biliary stents as the final method of internal biliary drainage were performed in 536 patients with obstructive cholestasis of malignant etiology. According to the type of the bile ducts stenting, the patients were divided into three groups. The first group consisted of 339 (63.3%) patients, endoscopic transpapillary stenting was performed by plastic stents. The second group included 140 (26.1%) patients with endoscopic stenting performed by self-expanding metal stents. The third group included 57 (10.6%) patients after antegrade stenting of the bile ducts. Results. After antegrade internal choleresis, we have got an accelerated rate of the bile ducts decompression. After transpapillary stenting of the bile ducts by metallic stents, a moderate tempo, and after transpapillary stenting of the bile ducts with plastic stents — slow decompression. Conclusion. The long-term results of the retrograde and the antegrade stenting of bile ducts with the use of self-expanding metal stents are comparable. The greatest amount of the unsatisfactory long-term results such as mechanical jaundice recurrence due to occlusion of the biliary stents, and the smallest median lifespan are noted after transpapillary stenting of the bile ducts by plastic stents.