Goals: to evaluate the efficacy of removal of suprasellar craniopharyngiomas in extended transsphenoid endoscopic endonasal surgeries. Materials and methods. The present study included 136 patients with various suprasellar (stalk and intra-extraventricular) craniopharyngiomas, who were operated at Burdenko Neurosergery Institut with the use of anterior expanded transsphenoid endoscopic endonasal access for the last 7 years. Patients are ranked by age, sex, size, growth and localization of the tumor. Results. Total removal of suprasellar craniopharyngiomas from anterior extended approaches was achieved in 71% patients. 89% of patients had vision improvement or no negative dynamics after surgery. Only 10% of patients have vision deterioration after surgery. In most cases, visual impairment is transient and is a consequence of the separation of tumor from the basal surface of the chiasma. The appearance or aggravation of hypopituitarism and insipidus diabetes symptoms after surgery has been noted in 43% of patients. Other serious postoperative complications include nasal liquorrhea — 8.8%, bacterial meningitis — 16%, mental disorders — 12.5%. The relapse rate was 12% with an average duration of a catamnesis of 38 months, lethality — 5.8%. Conclusions. Our findings indicate that removal of suprasellar craniopharyngiomas with advanced transsphenoid endoscopic endonasal operations is a highly effective and low-traumatic technique capable of providing a radical tumor removal along with a high quality of life after surgery, as well as relatively low rates of postoperative complications and lethality.