Aim. The objective of the present work was to study the epidemiological and clinical features of abdominal ischemic disease (AID) developing as a result of atherosclerotic lesions of the abdominal aorta and its unpaired visceral branches. Other goals included the elucidation of the character of the patients’ complaints, the role of the objective and instrumental examination in accordance with the level of proof, the analysis of the effectiveness of the non-pharmacological, pharmacological and endovascular methods of the treatment of the pathology in question. Material and methods. We carried out the clinical observation, determined the lipid composition of blood serum, measured the blood glucose level and transaminase activity. Also investigated were the morphological and functional characteristics of the digestive system in the patients experiencing compromised blood supply and perfusion concurrent with atherosclerotic stenosis of the unpaired visceral branches of the abdominal aorta. The study included 234 patients with this condition in whom the state of the vascular bed was evaluated by Doppler ultrasound examination, CT or MRI angiography, and aortography. The condition of the biological tissue of the stomach was studied with the use of the intragastric dual-frequency impedance technique. The comprehensive assessment of the functional state of hepatocytes, gall bladder, intra-extrahepatic bile ducts was carried out by dynamic scintigraphy of the liver. The condition of the pancreatic tissue was evaluated by ultrasound. Results. The study made it possible to identify various ischemic forms of abdominal visceropathies. The diagnostic criteria for ischemic visceropathies associated with the abdominal ischemic disease were defined and evidence obtained suggesting the heterogeneity of the clinical and functional disorders of the stomach, liver, pancreas, and intestines depending on the clinical stage of AIB. The results of the study confirm the effectiveness of the endovascular techniques employed for the correction of perfusion disorders of the digestive system and the role of comprehensive non-pharmacological and pharmacological lipid-lowering therapy in the prevention of both further progression of coronary atherosclerosis and the development of restenosis. Conclusion. We have distinguished two clinical morphological forms of abdominal ischemia, viz. abdominal visceralgia and abdominal ischemic visceralgia. The analysis of the methods for the surgical correction of either of these conditions has demonstrated the high effectiveness of the endovascular treatment of the patients presenting with the atherosclerotic lesions of the unpaired visceral arteries of the abdominal aorta with the clinical manifestations of abdominal ischemic disease.