Aim. The objective of the present work was to evaluate the prevalence of chronic abdominal ischemia in the patients presenting with abdominal pain syndrome and to study the specific clinical features of this condition. Material and methods. The study included 50 patients (36 women and 14 men). The inclusion criteria were as follows: the presence of abdominal pain syndrome, the age above 50 years, and consent of the patient to participate in the study. All the patients underwent Doppler ultrasound examination of the unpaired branches of abdominal aorta. Also, we undertook the quantitative and qualitative evaluation of the blood flow in order to detect circulatory inefficiency in mesenteric arteries. The GSRS questionnaire was used to evaluate the severity of clinical symptoms and the quality of life of the patients presenting with abdominal stenosis and confirmed stenosis of the celiac trunk and/or superior mesenteric artery. Results. The patients were divided into two groups. Group 1 was comprised of 9 (18%) patients with abdominal pain syndrome and the signs of hemodynamically significant stenosis of the unpaired visceral arteries. Group 2 consisted of 41 (82%) patients with abdominal pain syndrome in the absence of clinically significant disturbances of visceral Circulation. Eight patients in group 1 were found to have intravasal stenosis of the celiac trunk and/or superior mesenteric artery; one patient suffered extravasal compression of the celiac trunk by the adjacent diaphragmatic falciform ligament. The special analysis has demonstrated that the clinical picture in the patients of both groups, i.e. with stenosis and without circulatory disorders in the visceral arteries, was dominated by «dyspeptic syndrome» and «reflux syndrome». The comparison of characteristics of the patients of different groups obtained with the help of the GSRS questionnaire showed that the most common gastrointestinal pathology in those of group 1 was chronic pancreatitis followed by chronic atrophic gastritis and gastroesophageal reflux disease (GERD). Conclusion. The results of the study give evidence of the high frequency of hemodynamically significant disturbances visceral circulation in the patients of the middle and advanced age presenting with abdominal pain syndrome. The nosological structure of gastrointestinal diseases and concomitant pathological conditions is not significantly different in the patients with different hemodynamic patterns in the splanchnic basin with the exception of the enhanced frequency of gastroesophageal reflux disease in the patients with hemodynamically significant stenosis. However, three and more gastroesophageal diseases were significantly more frequently diagnosed in the patients of this group.