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Marukhov A.V.

Kirov Military Medical Academy

Khoroshilov S.E.

Negovsky Research Institute of General Reanimatology of the Federal Research and Clinical Center for Reanimatology and Rehabilitology;
Burdenko Main Military Clinical Hospital

Zakharov M.V.

Kirov Military Medical Academy

Nikulin A.V.

Negovsky Research Institute of General Reanimatology of the Federal Research and Clinical Center for Reanimatology and Rehabilitology;
Burdenko Main Military Clinical Hospital

Chubchenko N.V.

Kirov Military Medical Academy

Extracorporeal detoxification in complex treatment of severe acute pancreatitis

Authors:

Marukhov A.V., Khoroshilov S.E., Zakharov M.V., Nikulin A.V., Chubchenko N.V.

More about the authors

Journal: Russian Journal of Anesthesiology and Reanimatology. 2020;(5): 23‑29

DOI: 10.17116/anaesthesiology202005123

Read: 7772 times

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Table of contents

EXTRACORPOREAL DETOXIFICATION IN COMPLEX TREATMENT OF SEVERE ACUTE PANCREATITIS
EXTRACORPOREAL DETOXIFICATION IN COMPLEX TREATMENT OF SEVERE ACUTE PANCREATITIS

To cite this article:

Marukhov AV, Khoroshilov SE, Zakharov MV, Nikulin AV, Chubchenko NV. Extracorporeal detoxification in complex treatment of severe acute pancreatitis. Russian Journal of Anesthesiology and Reanimatology. 2020;(5):23‑29. (In Russ.)
https://doi.org/10.17116/anaesthesiology202005123

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Abstract:

Acute pancreatitis is one of the most life-threatening urgent surgical diseases. Mortality rate in severe acute pancreatitis is still high. Nevertheless, mortality is being decreased over the past decades. Endogenous intoxication is the main pathogenetic factor causing multiple organ failure in severe acute pancreatitis. Therefore, detoxification therapy is particularly important aspect in the complex treatment. Extracorporeal detoxification is potentially the most effective for endogenous intoxication and prevention of progression of multiple organ lesion. To date, clear approaches to these techniques have not been formed in the early phase of disease. We have analyzed literature data devoted to extracorporeal detoxification in severe acute pancreatitis and determined the recommendations for these techniques in intensive care.

Keywords:

severe acute pancreatitis
hemofiltration
hemodiafiltration
plasma exchange

Authors:

Marukhov A.V.

Kirov Military Medical Academy

Khoroshilov S.E.

Negovsky Research Institute of General Reanimatology of the Federal Research and Clinical Center for Reanimatology and Rehabilitology;
Burdenko Main Military Clinical Hospital

Zakharov M.V.

Kirov Military Medical Academy

Nikulin A.V.

Negovsky Research Institute of General Reanimatology of the Federal Research and Clinical Center for Reanimatology and Rehabilitology;
Burdenko Main Military Clinical Hospital

Chubchenko N.V.

Kirov Military Medical Academy

Received:

29.05.2020

Accepted:

15.06.2020

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