
Odontoidectomy: a systematic review
Журнал: Вопросы нейрохирургии имени Н.Н. Бурденко. 2026;90(3):107-114.
DOI: 10.17116/neiro202690031107
Read: 1147 раз
Abstract
There is extensive experience of odontoidectomies for various lesions of craniovertebral junction worldwide. Various approaches including those through natural anatomical openings (transoral and transnasal), as well as transcervical one is used.
OBJECTIVE
To compare the outcomes of odontoidectomies through various approaches according to literature data.
MATERIAL AND METHODS
A systematic review was conducted in accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. We reviewed the PubMed, Medline and Google Scholar databases using the keyword «odontoidectomy».
RESULTS
Analysis included 128 studies describing treatment outcomes in 688 patients. Transoral approach was used in 446 patients, transnasal — in 192, transcervical approach — in 50 patients.
CONCLUSION
Surgical approach for odontoidectomy significantly impacts surgery time, complication rates, initiation of oral feeding and length of hospital-stay.
Keywords
- odontoidectomy
- basilar impression
- transoral approach
- transnasal approach
Дата поступления: 16.10.2025
Дата принятия в печать: 12.03.2026
Дата публикации: 25.05.2026
- Botelho RV, Alves OL, Sá Carneiro G, Chen Z, Yaman O, Parthiban J, Visocchi M, Klekamp J, Goel A, Zileli M. Surgical Treatment of Basilar Invagination: WFNS Spine Committee Recommendations. Spine. 2025;50(11):751-759. https://doi.org/10.1097/BRS.0000000000005282
- Alijani B, Namin AK, Emamhadi M, Chabok SY, Behzadnia H, Haghani Dogahe M. Endoscopic Endonasal Approach to the Craniovertebral Junction Lesions: A Case Series of 18 Patients. Journal of Neurological Surgery Part B: Skull Base. 2023;84(15):499-506. https://doi.org/10.1055/a-1924-8268
- Chandra PS. Editorial: Are there any indications of transoral odontoidectomy today? Neurosurgical Focus: Video. 2020;3(1):V7. https://doi.org/10.3171/2020.4.FocusVid.20332
- Rennert RC, Stephens ML, Palmer AW, Rodriguez A, Kazemi N, Morris TW 3rd, Pait TG, Day JD. Basilar decompression via a far lateral transcondylar approach: technical note. Acta Neurochirurgica. 2022;164(10):2563-2572. https://doi.org/10.1007/s00701-022-05312-9
- Ariffin MH, Mohd-Mahdi SN, Baharudin A, M Tamil A, Abdul-Rhani S, Ibrahim K, Ng BW, Tan JA. Transtubular Transoral Approach for Irreducible Ventral Craniovertebral Junction Compressive Pathologies: Surgical Technique and Outcome. Malaysian Orthopaedic Journal. 2023;17(2):35-42. https://doi.org/10.5704/MOJ.2307.006
- Ye J, Liu B, Li J, Zheng G, Duan K, Gao L, Zhang C, Huang J, Tang Y. Full-endoscopic uniportal retropharyngeal odontoidectomy: A preliminary case report. Frontiers in Surgery. 2023;9:973064. https://doi.org/10.3389/fsurg.2022.973064
- Chen Z, Bi Z, Liu D, Deng B, Lu M, Zeng Y, Zhang X, Lin T. Endoscopic transnasal and transoral resection of the odontoid process and C1 combined with occipitocervical fusion for osteoradionecrosis of the upper cervical spine: a case report and literature review. BMC Neurology. 2024;24(1):421. https://doi.org/10.1186/s12883-024-03928-1
- Zainudin NA, Muhamad Ariffin MH. A Transoral Approach to Decompression Odontoidectomy With Posterior Wiring and Fusion for Pediatric Platybasia With Chiari Malformation. Cureus. 2024;16(6):e62754. https://doi.org/10.7759/cureus.62754
- Kassam AB, Snyderman C, Gardner P, Carrau R, Spiro R. The Expanded Endonasal Approach: A Fully Endoscopic Transnasal Approach and Resection of the Odontoid Process: Technical Case Report. Neurosurgery. 2005;57(1 Suppl):E213; discussion E213. https://doi.org/10.1227/01.NEU.0000163687.64774.E4
- Chernov IV, Shkarubo AN, Konyashin DA, Andreev DN. Transoral approach in surgery for chordomas extending into craniovertebral junction: a systematic review of the literature. Burdenko’s Journal of Neurosurgery. 2024;88(3):111-119. (In Russ., In Engl.). https://doi.org/10.17116/neiro202488031111
- Gstrein NA, Zwicky S, Serra C, Hugelshofer M, Regli L, Soyka MB, Holzmann D, Meerwein CM. Rhinologic outcome of endoscopic transnasal-transsphenoidal pituitary surgery: an institutional series, systematic review, and meta-analysis. European Archives of Oto-Rhino-Laryngology. 2023;280(9):4091-4099. https://doi.org/10.1007/s00405-023-07934-w
- Shkarubo AN, Nazarenko AG, Chernov IV, Andreev DN, Kuleshov AA, Konovalov NA, Lisyanskiy IN, Sinelnikov ME. Comparative analysis of endoscopic transnasal and microsurgical transoral odontoidectomy: Literature review and own experience. N.N. Priorov Journal of Traumatology and Orthopedics. 2023;30(1):41-62. (In Russ, In Engl.). https://doi.org/10.17816/vto321930
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