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Lisitsky I.Yu.

Sechenov First Moscow State Medical University

Lychagin A.V.

Sechenov First Moscow State Medical University

Zarov A.Yu.

Sechenov First Moscow State Medical University

Korkunov A.L.

Sechenov First Moscow State Medical University

Cherepanov V.G.

Sechenov First Moscow State Medical University

Vyzankin I.A.

Sechenov First Moscow State Medical University

Successful surgical treatment of patient with cervical myelopathy due to ossification of the posterior longitudinal ligament: a rare clinical observation and literature review

Authors:

Lisitsky I.Yu., Lychagin A.V., Zarov A.Yu., Korkunov A.L., Cherepanov V.G., Vyzankin I.A.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2021;85(4): 69‑76

DOI: 10.17116/neiro20218504169

Read: 4479 times

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Table of contents

SUCCESSFUL SURGICAL TREATMENT OF PATIENT WITH CERVICAL MYELOPATHY DUE TO OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENT: A RARE CLINICAL OBSERVATION AND LITERATURE REVIEW
SUCCESSFUL SURGICAL TREATMENT OF PATIENT WITH CERVICAL MYELOPATHY DUE TO OSSIFICATION OF THE POSTERIOR LONGITUDINAL LIGAMENT: A RARE CLINICAL OBSERVATION AND LITERATURE REVIEW

To cite this article:

Lisitsky IYu, Lychagin AV, Zarov AYu, Korkunov AL, Cherepanov VG, Vyzankin IA. Successful surgical treatment of patient with cervical myelopathy due to ossification of the posterior longitudinal ligament: a rare clinical observation and literature review. Burdenko's Journal of Neurosurgery. 2021;85(4):69‑76. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20218504169

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The authors describe the result of combined surgical treatment of a patient with symptomatic multiple-level cervical spine stenosis following ossification of posterior longitudinal ligament. The first stage included decompressive laminectomy and cervical spine fusion using a screw. At the second stage, CIV—CV—CVI—CVII corporectomy with total resection of the ossified posterior longitudinal ligament and CIII—ThI corporodesis with a bone autograft were carried out. This approach was valuable to minimize the risk of iatrogenic damage to the spinal cord, eliminate long spinal stenosis and perform circular fusion of the cervical spine. These measures led to regression of cervical myelopathy symptoms. A brief review is presented.

Keywords:

ossification of posterior longitudinal ligament
multiple-level stenosis of the cervical spine
cervical myelopathy
combined surgery

Authors:

Lisitsky I.Yu.

Sechenov First Moscow State Medical University

Lychagin A.V.

Sechenov First Moscow State Medical University

Zarov A.Yu.

Sechenov First Moscow State Medical University

Korkunov A.L.

Sechenov First Moscow State Medical University

Cherepanov V.G.

Sechenov First Moscow State Medical University

Vyzankin I.A.

Sechenov First Moscow State Medical University

Received:

21.05.2020

Accepted:

28.05.2021

Close metadata

References:

  1. Tsukimoto H. A case report: autopsy of syndrome of compression of spinal cord owing to ossification within spinal canal of cervical spines. Nippon Geka Hokan (Archiv für Japanische Chirurgie). 1960;29:1003-1007.
  2. Tsuyama N. Ossification of the posterior longitudinal ligament of the spine. Clinical Orthopaedics and Related Research. 1984;184:71-84. 
  3. Wang MY, Thambuswamy M. Ossification of the posterior longitudinal ligament in non-Asians: demographic, clinical, and radiographic findings in 43 patients. Neurosurgical Focus. 2011;30(3):E4.  https://doi.org/10.3171/2010.12.FOCUS10277
  4. Abiola R, Rubery P, Mesfin A. Ossification of the posterior longitudinal ligament: etiology, diagnosis, and outcomes of nonoperative and operative management. Global Spine Journal. 2016;6(2):195-204.  https://doi.org/10.1055/s-0035-1556580
  5. Tahara M, Aiba A, Yamazaki M, Ikeda Y, Goto S, Moriya H, Okawa A. The extent of ossification of posterior longitudinal ligament of the spine associated with nucleotide pyrophosphatase gene and leptin receptor gene polymorphisms. Spine (Phila Pa 1976). 2005;30:877-880.  https://doi.org/10.1097/01.brs.0000160686.18321.ad
  6. Yonemori K, Imamura T, Ishidou Y, Okano T, Matsunaga S, Yoshida H, Kato M, Sampath TK, Miyazono K, ten Dijke P, Sakou T. Bone morphogenetic protein receptors and activin receptors are highly expressed in ossified ligament tissues of patients with ossification of the posterior longitudinal ligament. The American Journal of Pathology. 1997;150(4):1335-1347.
  7. Ono K, Yonenobu K, Miyamoto S, Okada K. Pathology of ossification of the posterior longitudinal ligament and ligamentum flavum. Clinical Orthopaedics and Related Research. 1999;359:18-26.  https://doi.org/10.1097/00003086-199902000-00003
  8. Ehara S, Shimamura T, Nakamura R, Yamazaki K. Paravertebral ligamentous ossification: DISH, OPLL and OLF. European Journal of Radiology. 1998;27(3):196-205.  https://doi.org/10.1016/s0720-048x(97)00164-2
  9. Smith ZA, Buchanan CC, Raphael D, Khoo LT. Ossification of the posterior longitudinal ligament: pathogenesis, management, and current surgical approaches. A review. Neurosurgical Focus. 2011;30(3):E10.  https://doi.org/10.3171/2011.1.FOCUS10256
  10. Fujiyoshi T, Yamazaki M, Kawabe J, Endo T, Furuya T, Koda M, Okawa A, Takahashi K, Konishi H. A new concept for making decisions regarding the surgical approach for cervical ossification of the posterior longitudinal ligament: the K-line. Spine (Phila Pa 1976). 2008;33(26):990-993.  https://doi.org/10.1097/BRS.0b013e318188b300
  11. Kim B, Yoon DH, Shin HC, Kim KN, Yi S, Shin DA, Ha Y. Surgical outcome and prognostic factors of anterior decompression and fusion for cervical compressive myelopathy due to ossification of the posterior longitudinal ligament. Spine. 2015;15(5):875-884.  https://doi.org/10.1016/j.spinee.2015.01.028
  12. Sakai K, Okawa A, Takahashi M, Arai Y, Kawabata S, Enomoto M, Kato T, Hirai T, Shinomiya K. Five-year follow-up evaluation of surgical treatment for cervical myelopathy caused by ossification of the posterior longitudinal ligament: a prospective comparative study of anterior decompression and fusion with floating method versus laminoplasty. Spine (Phila Pa 1976). 2012;37(5):367-376.  https://doi.org/10.1097/BRS.0b013e31821f4a51
  13. Weijun Liu, Ling Hu, Po-Hsin Chou, Ming Liu, Wusheng Kan, Junwen Wang. Comparison of anterior decompression and fusion versus laminoplasty in the treatment of multilevel cervical ossification of the posterior longitudinal ligament: a systematic review and meta-analysis. Therapeutics and Clinical Risk Management. 2016;12:675-685.  https://doi.org/10.2147/TCRM.S100046
  14. Lee CH, Sohn MJ, Lee CH, Choi CY, Han SR, Choi BW. Are there differences in the progression of ossification of the posterior longitudinal ligament following laminoplasty versus fusion?: a meta-analysis. Spine (Phila Pa 1976). 2017;42(12):887-894.  https://doi.org/10.1097/BRS.0000000000001933
  15. Feng F, Ruan W, Liu Z, Li Y, Cai L. Anterior versus posterior approach for the treatment of cervical compressive myelopathy due to ossification of the posterior longitudinal ligament: A systematic review and meta-analysis. International Journal of Surgery. 2016;27:26-33.  https://doi.org/10.1016/j.ijsu.2016.01.038
  16. Li H, Dai LY. A systematic review of complications in cervical spine surgery for ossification of the posterior longitudinal ligament. Spine. 2011;11(11):1049-1057. https://doi.org/10.1016/j.spinee.2011.09.008
  17. Yamaura I, Kurosa Y, Matuoka T, Shindo S. Anterior floating method for cervical myelopathy caused by ossification of the posterior longitudinal ligament. Clinical Orthopaedics and Related Research. 1999;359:27-34.  https://doi.org/10.1097/00003086-199902000-00004
  18. Lee DH, Cho JH, Lee CS, Hwang CJ, Choi SH, Hong CG. A novel anterior decompression technique (vertebral body sliding osteotomy) for ossification of posterior longitudinal ligament of the cervical spine. Spine. 2018;18(6):1099-1105. https://doi.org/10.1016/j.spinee.2018.02.022
  19. Dalbayrak S, Yilmaz M, Naderi S. «Skip» corpectomy in the treatment of multilevel cervical spondylotic myelopathy and ossified posterior longitudinal ligament. Technical note. Journal of Neurosurgery. Spine. 2010;12(1):33-38.  https://doi.org/10.3171/2009.7.SPINE08965
  20. Kim K, Isu T, Morimoto D, Sugawara A, Kobayashi S, Teramoto A. Cervical anterior fusion with the Williams-Isu method: clinical review. Journal of Nippon Medical School. 2012;79(1):37-45.  https://doi.org/10.1272/jnms.79.37
  21. Goel A, Pareikh S. Limited oblique corpectomy for treatment of ossified posterior longitudinal ligament. Neurology India. 2005;53(3):280-282.  https://doi.org/10.4103/0028-3886.16922
  22. Lee SH, Kim KT, Lee JH, Kang KC, Jang SJ, Hwang SP, Yoon KT. 540° Cervical realignment procedure for extensive cervical OPLL with kyphotic deformity. Spine (Phila Pa 1976). 2016;41(24):1876-1883. https://doi.org/10.1097/brs.0000000000001794
  23. Son S, Lee SG, Yoo CJ, Park CW, Kim WK. Single stage circumferential cervical surgery (selective anterior cervical corpectomy with fusion and laminoplasty) for multilevel ossification of the posterior longitudinal ligament with spinal cord ischemia on MRI. Journal of Korean Neurosurgical Society. 2010;48(4):335-341.  https://doi.org/10.3340/jkns.2010.48.4.335
  24. Arima H, Naito K, Yamagata T, Kawahara S, Ohata K, Takami T. Anterior and posterior segmental decompression and fusion for severely localized ossification of the posterior longitudinal ligament of the cervical spine: technical note. Neurologia Medico-Chirurgica. 2019;59(6):238-245.  https://doi.org/10.2176/nmc.tn.2018-0324
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