The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Kirilochev O.O.

Astrakhan State Medical University, Astrakhan, Russia;
Astrakhan Regional Clinical Psychiatric Hospital, Astrakhan, Russia

Umerova A.R.

Astrakhan State Medical University, Astrakhan, Russia

Dorfman I.P.

Astrakhan State Medical University, Astrakhan, Russia

Khryashchev A.V.

Astrakhan State Medical University, Astrakhan, Russia;
Astrakhan Regional Clinical Psychiatric Hospital, Astrakhan, Russia

The drug-drug interactions in a psychiatric hospital

Authors:

Kirilochev O.O., Umerova A.R., Dorfman I.P., Khryashchev A.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(5): 26‑30

DOI: 10.17116/jnevro20171175126-30

Read: 3453 times

Download PDF (RU)
Contact the author
Table of contents

THE DRUG-DRUG INTERACTIONS IN A PSYCHIATRIC HOSPITAL
THE DRUG-DRUG INTERACTIONS IN A PSYCHIATRIC HOSPITAL

To cite this article:

Kirilochev OO, Umerova AR, Dorfman IP, Khryashchev AV. The drug-drug interactions in a psychiatric hospital. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(5):26‑30. (In Russ.)
https://doi.org/10.17116/jnevro20171175126-30

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова (S.S. Korsakov Journal of Neurology and Psychiatry)
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Therapies for focal epilepsy asso­ciated with brain tumors. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(9):14-20
Abstract:

An analysis of 132 drugs used in a psychiatric hospital for the estimation of the possibility of drug-drug interactions has been carried out. It has been established that one in five potential combination has a drug-drug interaction with clinically significant interactions being more frequent. Psychotropic drugs occupy a leading position in the number of such interactions. This analysis is able to improve the safety of the combined pharmacotherapies by choosing an alternative drug, correction of dose or active monitoring of the clinical condition of the patient, including laboratory and instrumental data.

Keywords:

combined pharmacotherapies
drug-drug interactions
adverse drug reactions

Authors:

Kirilochev O.O.

Astrakhan State Medical University, Astrakhan, Russia;
Astrakhan Regional Clinical Psychiatric Hospital, Astrakhan, Russia

Umerova A.R.

Astrakhan State Medical University, Astrakhan, Russia

Dorfman I.P.

Astrakhan State Medical University, Astrakhan, Russia

Khryashchev A.V.

Astrakhan State Medical University, Astrakhan, Russia;
Astrakhan Regional Clinical Psychiatric Hospital, Astrakhan, Russia

Close metadata

References:

  1. Otdelenov VA, Novakova AI, Karasev AV, Yashina LP, Payuschik SA, Sychev DA, Kleimenova EB, Nazarenko GI. Estimation of the incidence of potentially significant drug-drug interactions in patients with polypharmacy in the general hospital. Klinicheskaya farmakologiya i terapiya. 2012;21(5):81-85. (In Russ.).
  2. Längle G, Steinert T, Weiser P, Schepp W, Jaeger S, Pfiffner C, Frasch K, Eschweiler GW, Messer T, Croissant D, Becker T, Kilian R. Effects of polypharmacy on outcome in patients with schizophrenia in routine psychiatric treatment. Acta Psychiatrica Scandinavica. 2012;125(5):372-381. doi:10.1111/j.1600-0447.2012.01835.x
  3. Sychev D, Otdelenov V, Danilina K, Anikin G, Arslanbekova S. Drug interactions and polypragmasy in a physician’s practice. Vrach. 2013;5:5-9. (In Russ.).
  4. Sychev DA, Otdelenov VA. Drug—drug interactions in the practice of an internist: The opinion of a clinical pharmacologist. Spravochnik Poliklinicheskogo Vracha. 2014;12:18-21. (In Russ.).
  5. Kazakov AS. The determination of confidence of cause-and-effect relation «untoward reaction-medicinal agents'' interaction. Russkii meditsinskii zhurnal. 2013;5:38-43. (In Russ.).
  6. Kantemirova BI, Timofeeva NV, Griganov VI, Shilova AA. The problem of undesirable side reactions of drugs. Astrakhanskii meditsinskii zhurnal. 2011;6(4):8-12. (In Russ.).
  7. Stepanova NA, Streltsova EN, Galimzyanov KhM, Kantemirova BI. Unfavourable side effects to anti-TB drugs in newly diagnosed patients with lung tuberculosis Astrakhanskii meditsinskii zhurnal. 2011;9(4):66-71. (In Russ.).
  8. Syunyakov T. Drug-drug intetactions during antipsychotic treatment of schizophrenia: safe and dangerous combinations of drugs. Sovremennaya terapiya psikhicheskikh rasstroistv. 2013;1:11-14. (In Russ.).
  9. Guo JJ, Wu J, Kelton CM, Jing Y, Fan H, Keck PE, Patel NC. Exposure to potentially dangerous drug-drug interactions involving antipsychotics. Psychiatric Services. 2012;63(11):1080-1088. doi:10.1176/appi.ps.201100443
  10. Teixeira JJ, Crozatti MT, dos Santos CA, Romano-Lieber NS. Potential drug-drug interactions in prescriptions to patients over 45 years of age in primary care, southern Brazil. PLoS One. 2012;7(10):47062. doi:10.1371/journal.pone.0047062
  11. Laursen TM, Munk-Olsen T, Vestergaard M. Life expectancy and cardiovascular mortality in persons with schizophrenia. Current Opinion in Psychiatry. 2012;25(2):83-88. doi:10.1097/YCO.0b013e32835035ca
  12. Magro L, Moretti U, Leone R. Epidemiology and characteristics of adverse drug reactions caused by drug-drug interactions. Expert Opinion on Drug Safety. 2012;11(1):83-94. doi:10.1517/14740338.2012.631910
  13. Murtaza G, Khan MY, Azhar S, Khan SA, Khan TM. Assessment of potential drug-drug interactions and its associated factors in the hospitalized cardiac patients. Saudi Pharmaceutical Journal. 2016;24(2):220-225. doi:10.1016/j.jsps.2015.03.009
  14. Oertle M. Frequency and nature of drug-drug interactions in a Swiss primary and secondary acute care hospital. Swiss Medical Weekly. 2012;142:13522. doi:10.4414/smw.2012.13522
  15. URL: http://www.drugs.com/drug_interactions.php Access date: 01.10.2016.
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.