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Balashov A.M.

Nauchnyĭ tsentr psikhicheskogo zdorov'ia RAMN, Rossiĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Moskva

Neurosteroids and addictive pathology

Authors:

Balashov A.M.

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To cite this article:

Balashov AM. Neurosteroids and addictive pathology. S.S. Korsakov Journal of Neurology and Psychiatry. 2010;110(6):107‑111. (In Russ.)

References:

  1. Balashov A.M. Endogennye allostericheskie regulyatory retseptorov. Uspekhi fiziol nauk 2004; 35: 2: 73-91.
  2. Balashov A.M. Sistema GAMK i alkogol': sushchestvuet li «etanol'nyi retseptor»? Zhurn nevropatol i psikhiat 2007; Alkogolizm (prilozhenie k zhurnalu) 1: 56-62.
  3. Ahboucha S., Coyne L., Hirakawa R. et al. An interaction between benzodiazepines and neuroactive steroids at GABA A receptors in cultured hippocampal neurons. Neurochem Int 2006; 48: 8: 703-707.
  4. Barbaccia M.L., Affricano D., Trabucchi M. et al. Ethanol markedly increases "GABAergic" neurosteroids in alcohol-preferring rats. Eur J Pharmacol 1999; 384: 2-3: R1-2.
  5. Barbosa A.D., Morato G.S. Effect of epipregnanolone and pregnenolone sulfate on chronic tolerance to ethanol. Pharmacol Biochem Behav 2000; 67: 3: 459-464.
  6. Barbosa A.D., Morato G.S. Pregnenolone sulfate, dehydroepiandrosterone sulfate and allotetrahydrodeoxycorticosterone affect rapid tolerance to the hypothermic effect of ethanol. Brain Res Bull 2002; 58: 1: 99-105.
  7. Barrot M., Vallée M., Gingras M.A. et al. The neurosteroid pregnenolone sulphate increases dopamine release and the dopaminergic response to morphine in the rat nucleus accumbens. Eur J Neurosci 1999; 11: 10: 3757-3760.
  8. Bienkowski P., Kostowski W. Discriminative stimulus properties of ethanol in the rat: effects of neurosteroids and picrotoxin. Brain Res 1997; 753: 2: 348-352.
  9. Biggio G., Concas A., Follesa P. et al. Stress, ethanol, and neuroactive steroids. Pharmacol Ther 2007; 116: 1: 140-171.
  10. Budziszewska B., Jaworska-Feil L., Lasoń W. Neurosteroids and the naloxone-precipitated withdrawal syndrome in morphine-dependent mice. Eur Neuropsychopharmacol 1996; 6: 2: 135-140.
  11. Cagetti E., Pinna G., Guidotti A. et al. Chronic intermittent ethanol (CIE) administration in rats decreases levels of neurosteroids in hippocampus, accompanied by altered behavioral responses to neurosteroids and memory function. Neuropharmacology 2004; 46: 4: 570-579.
  12. Concas A., Sogliano C., Porcu P. et al. Neurosteroids in nicotine and morphine dependence. Psychopharmacology (Berl) 2006; 186: 3: 281-292.
  13. Costa E.T., Olivera D.S., Meyer D.A. et al. Fetal alcohol exposure alters neurosteroid modulation of hippocampal N-methyl-D-aspartate receptors. J Biol Chem 2000; 275: 49: 38268-38274.
  14. Criswell H.E., McCown T.J., Ming Z. et al. Interactive role for neurosteroids in ethanol enhancement of gamma-aminobutyric acid-gated currents from dissociated substantia nigra reticulata neurons. J Pharmacol Exp Ther 1999; 291: 3: 1054-1059.
  15. Do-Rego J.L., Mensah-Nyagan A.G., Beaujean D. et al. The octadecaneuropeptide ODN stimulates neurosteroid biosynthesis through activation of central-type benzodiazepine receptors. J Neurochem 2001; 76: 1: 128-138.
  16. Doron R., Fridman L., Gispan-Herman I. et al. DHEA, a neurosteroid, decreases cocaine self-administration and reinstatement of cocaine-seeking behavior in rats. Neuropsychopharmacology 2006; 31: 10: 2231-2236.
  17. Dubrovsky B.O. Steroids, neuroactive steroids and neurosteroids in psychopathology. Prog Neuropsychopharmacol Biol Psychiat 2005; 29: 2: 169-192.
  18. Engel S.R., Purdy R.H., Grant K.A. Characterization of discriminative stimulus effects of the neuroactive steroid pregnanolone. J Pharmacol Exp Ther 2001; 297: 2: 489-495.
  19. Filip M., Nowak E., Siwanowicz J., Przegaliński E. Effects of corticosterone and its synthesis blockade on the cocaine-induced discriminative stimulus effects in rats. Pol J Pharmacol 2000; 52: 6: 411-421.
  20. Finn D.A., Sinnott R.S., Ford M.M. et al. Sex differences in the effect of ethanol injection and consumption on brain allopregnanolone levels in C57BL/6 mice. Neuroscience 2004; 123: 4: 813-819.
  21. Follesa P., Biggio F., Talani G. et al. Neurosteroids, GABAA receptors, and ethanol dependence. Psychopharmacology (Berl) 2006; 186: 3: 267-280.
  22. Ford M.M., Nickel J.D., Finn D.A. Treatment with and withdrawal from finasteride alter ethanol intake patterns in male C57BL/6J mice: potential role of endogenous neurosteroids? Alcohol 2005; 37: 1: 23-33.
  23. Ford M.M., Nickel J.D., Phillips T.J., Finn D.A. Neurosteroid modulators of GABA(A) receptors differentially modulate ethanol intake patterns in male C57BL/6J mice. Alcohol Clin Exp Res 2005; 29: 9: 1630-1640.
  24. Gambhir M., Mediratta P.K., Sharma K.K. Evaluation of the analgesic effect of neurosteroids and their possible mechanism of action. Indian J Physiol Pharmacol 2002; 46: 2: 202-208.
  25. Goodchild C.S., Robinson A., Nadeson R. Antinociceptive properties of neurosteroids IV: pilot study demonstrating the analgesic effects of alphadolone administered orally to humans. Br J Anaesth 2001; 86: 4: 528-534.
  26. Gulinello M., Smith S.S. Anxiogenic effects of neurosteroid exposure: sex differences and altered GABAA receptor pharmacology in adult rats. J Pharmacol Exp Ther 2003; 305: 2: 541-548.
  27. Hayashi T., Su T.P. Regulating ankyrin dynamics: Roles of sigma-1 receptors. Proc Natl Acad Sci USA 2001; 98: 2: 491-496.
  28. Iancu I., Tchernihovsky E., Maayan R. et al. Circulatory neurosteroid levels in smoking and non-smoking chronic schizophrenia patients. Eur Neuropsychopharmacol 2007; 17: 8: 541-545.
  29. Izumi Y., Murayama K., Tokuda K. et al. GABAergic neurosteroids mediate the effects of ethanol on long-term potentiation in rat hippocampal slices. Eur J Neurosci 2007; 26: 7: 1881-1888.
  30. Kang M.H., Spigelman I., Olsen R.W. Alteration in the sensitivity of GABA(A) receptors to allosteric modulatory drugs in rat hippocampus after chronic intermittent ethanol treatment. Alcohol Clin Exp Res 1998; 22: 9: 2165-2173.
  31. Kellogg C.K., Kenjarski T.P., Pleger G.L., Frye C.A. Region-, age-, and sex-specific effects of fetal diazepam exposure on the postnatal development of neurosteroids. Brain Res 2006; 1067: 1: 115-125.
  32. Kostowski W., Bieńkowski P. Discriminative stimulus effects of ethanol: neuropharmacological characterization. Alcohol 1999; 17: 1: 63-80.
  33. Lamba V., Yasuda K., Lamba J.K. et al. PXR (NR1I2): splice variants in human tissues, including brain, and identification of neurosteroids and nicotine as PXR activators. Toxicol Appl Pharmacol 2004; 199: 3: 251-265.
  34. Martín-García E., Pallarès M. The neurosteroid pregnenolone sulfate neutralized the learning impairment induced by intrahippocampal nicotine in alcohol-drinking rats. Neuroscience 2005; 136: 4: 1109-1119.
  35. Martín-García E., Pallarès M. The intrahippocampal administration of the neurosteroid allopregnanolone blocks the audiogenic seizures induced by nicotine. Brain Res 2005; 1062: 1-2: 144-150.
  36. Martín-García E., Darbra S., Pallarès M. Intrahippocampal allopregnanolone decreases voluntary chronic alcohol consumption in non-selected rats. Prog Neuropsychopharmacol Biol Psychiat 2007; 31: 4: 823-831.
  37. O'Dell L.E., Alomary A.A., Vallée M. et al. Ethanol-induced increases in neuroactive steroids in the rat brain and plasma are absent in adrenalectomized and gonadectomized rats. Eur J Pharmacol 2004; 484: 2-3: 241-247.
  38. Reddy D.S., Kulkarni S.K. Chronic neurosteroid treatment prevents the development of morphine tolerance and attenuates abstinence behavior in mice. Eur J Pharmacol 1997; 337: 1: 19-25.
  39. Romieu P., Lucas M., Maurice T. Sigma1 receptor ligands and related neuroactive steroids interfere with the cocaine-induced state of memory. Neuropsychopharmacology 2006; 31: 7: 1431-1443.
  40. Rougé-Pont F., Mayo W., Marinelli M. et al. The neurosteroid allopregnanolone increases dopamine release and dopaminergic response to morphine in the rat nucleus accumbens. Eur J Neurosci 2002; 16: 1: 169-173.
  41. Schumacher M., Baulieu E.E. Neurosteroids: synthesis and functions in the central and peripheral nervous systems. Ciba Found Symp 1995; 191: 90-106.
  42. Shannon E.E., Shelton K.L., Vivian J.A. et al. Discriminative stimulus effects of ethanol in mice lacking the gamma-aminobutyric acid type A receptor delta subunit. Alcohol Clin Exp Res 2004; 28: 6: 906-913.
  43. Shannon E.E., Porcu P., Purdy R.H., Grant K.A. Characterization of the discriminative stimulus effects of the neuroactive steroid pregnanolone in DBA/2J and C57BL/6J inbred mice. J Pharmacol Exp Ther 2005; 314: 2: 675-685.
  44. Sharma A.N., Chopde C.T., Hirani K. et al. Chronic progesterone treatment augments while dehydroepiandrosterone sulphate prevents tolerance to ethanol anxiolysis and withdrawal anxiety in rats. Eur J Pharmacol 2007; 567: 3: 211-222.
  45. Sinnott R.S., Mark G.P., Finn D.A. Reinforcing effects of the neurosteroid allopregnanolone in rats. Pharmacol Biochem Behav 2002; 72: 4: 923-929.
  46. Stoffel-Wagner B. Neurosteroid biosynthesis in the human brain and its clinical implications. Ann NY Acad Sci 2003; 1007: 64-78.
  47. Su T.P., Hayashi T. Understanding the molecular mechanism of sigma-1 receptors: towards a hypothesis that sigma-1 receptors are intracellular amplifiers for signal transduction. Curr Med Chem 2003; 10: 20: 2073-2080.
  48. Vallée M., Mayo W., Koob G.F., Le Moal M. Neurosteroids in learning and memory processes. Int Rev Neurobiol 2001; 46: 273-320.
  49. Vanover K.E., Suruki M., Robledo S. et al. Positive allosteric modulators of the GABA(A) receptor: differential interaction of benzodiazepines and neuroactive steroids with ethanol. Psychopharmacology (Berl) 1999; 141: 1: 77-82.
  50. Wang N., Wu H.H., Hou Y.N. Effects of morphine dependence on the levels of neurosteroids in rat brain. Yao Xue Xue Bao 2005; 40: 11: 1037-1040.
  51. Winter L., Nadeson R., Tucker A.P., Goodchild C.S. Antinociceptive properties of neurosteroids: a comparison of alphadolone and alphaxalone in potentiation of opioid antinociception. Anesth Analg 2003; 97: 3: 798-805.
  52. Yan C.Z., Hou Y.N. Effects of morphine dependence and withdrawal on levels of neurosteroids in rat brain. Acta Pharmacol Sin 2004; 25: 10: 1285-1291.

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