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Zakroyshchikova I.V.

Research center of Neurology

Askarova L.Sh.

Research center of Neurology

Bryukhov V.V.

Research Center of Neurology

Anufriev P.L.

Research Center of Neurology

Kozlova A.O.

Research center of Neurology

Zakharova M.N.

Research Center of Neurology

Acute hemorrhagic leukoencephalitis with a subacute onset

Authors:

Zakroyshchikova I.V., Askarova L.Sh., Bryukhov V.V., Anufriev P.L., Kozlova A.O., Zakharova M.N.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(7‑2): 116‑121

DOI: 10.17116/jnevro2023123072116

Read: 7863 times

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Table of contents

ACUTE HEMORRHAGIC LEUKOENCEPHALITIS WITH A SUBACUTE ONSET
ACUTE HEMORRHAGIC LEUKOENCEPHALITIS WITH A SUBACUTE ONSET

To cite this article:

Zakroyshchikova IV, Askarova LSh, Bryukhov VV, Anufriev PL, Kozlova AO, Zakharova MN. Acute hemorrhagic leukoencephalitis with a subacute onset. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;123(7‑2):116‑121. (In Russ.)
https://doi.org/10.17116/jnevro2023123072116

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Abstract:

Acute hemorrhagic leukoencephalitis (AHLE), also called Hurst’s encephalitis, is a rare demyelinating disease of the central nervous system characterized by rapid progression and acute inflammation of the white matter of the brain and spinal cord. AHLE is currently considered as a rare, most severe variant of acute disseminated encephalomyelitis. Clinically AHLE is characterized by a fulminant course with a rapid development of encephalopathy and multifocal neurological symptoms. AHLE is associated with high mortality rate that requires immediate and aggressive treatment initiation. This article describes a case of AHLE with an atypical course, a subacute form, which is extremely rarely described in the literature, with the progressive symptoms’ development over several months. Due to delayed treatment initiation, unfortunately, a fatal outcome has been observed. Subsequent histological examination of the autopsy material confirmed the presence of a subacute form of AHLE in the patient.

Keywords:

acute hemorrhagic leukoencephalitis
Hurst’s encephalitis
subacute onset
demyelinating disease

Authors:

Zakroyshchikova I.V.

Research center of Neurology

Askarova L.Sh.

Research center of Neurology

Bryukhov V.V.

Research Center of Neurology

Anufriev P.L.

Research Center of Neurology

Kozlova A.O.

Research center of Neurology

Zakharova M.N.

Research Center of Neurology

Received:

10.05.2023

Accepted:

23.05.2023

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References:

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