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Egorov V.I.

Moscow Regional Clinical Research Institute named after M.F. Vladimirsky

Ryazantsev S.V.

Saint-Petersburg Research Institute of Ear, Throat, Nose and Speech

Kozarenko A.V.

Moscow Regional Scientific Research Clinical Institute MF Vladimirsky

Lilenko S.V.

Saint Petersburg ENT and Speech Research Institute;
North-Western State Medical University named after I.I. Mechnikov

Kozarenko M.A.

Saint-Petersburg Research Institute of Ear, Throat, Nose and Speech

Pol’schikova A.Yu.

Moscow Regional Scientific Research Clinical Institute MF Vladimirsky

Peculiarities of differential diagnostics of perilymphatic fistulas of the labyrinth windows of non-inflammatory genesis

Authors:

Egorov V.I., Ryazantsev S.V., Kozarenko A.V., Lilenko S.V., Kozarenko M.A., Pol’schikova A.Yu.

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Journal: Russian Bulletin of Otorhinolaryngology. 2021;86(4): 17‑22

DOI: 10.17116/otorino20218604117

Read: 1335 times

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PECULIARITIES OF DIFFERENTIAL DIAGNOSTICS OF PERILYMPHATIC FISTULAS OF THE LABYRINTH WINDOWS OF NON-INFLAMMATORY GENESIS
PECULIARITIES OF DIFFERENTIAL DIAGNOSTICS OF PERILYMPHATIC FISTULAS OF THE LABYRINTH WINDOWS OF NON-INFLAMMATORY GENESIS

To cite this article:

Egorov VI, Ryazantsev SV, Kozarenko AV, Lilenko SV, Kozarenko MA, Pol’schikova AYu. Peculiarities of differential diagnostics of perilymphatic fistulas of the labyrinth windows of non-inflammatory genesis. Russian Bulletin of Otorhinolaryngology. 2021;86(4):17‑22. (In Russ.)
https://doi.org/10.17116/otorino20218604117

Подписка 2025-2 (Russian Bulletin of Otorhinolaryngology)
 
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THE PURPOSE OF THE STUDY

To determine the value of the results of various audiological and vestibulometric studies for the differential diagnosis of non-inflammatory perilymphatic fistulas of the labyrinth windows (PFOLW).

MATERIAL AND METHODS

The retrospective and prospective analysis of the informative value of the results of audiological and vestibulometric studies was carried out in 124 people with different combinations of cochleovestibular complaints, who had different pathology of the inner and middle ear, with different terms of the disease — from several days to 30 years. To assess the informativeness of the applied testing, the following operational characteristics were determined: general sensitivity (Se), specificity (Sp) and the prognostic value of a positive result (PPV=positive predictive value). A pair-by-pair comparison of the prognostic value of a positive result of vestibulometric and audiometric tests was performed using the Pearson criterion χ2 and the exact Fisher criterion.

RESULTS

It is shown that none of the tests used has 100% reliability, but the consistent application of some of them can successfully improve the diagnosis of idiopathic PFOL. When comparing the results of a number of tests, such as the Fukuda walking test and / or the Babinsky—Weil walking test, audiometric tests with head clone and hyperventilation, the test of fluid injection into the external auditory canal and the test of J. Frasser & L. Flood, it was found that the average prognostic value of a positive result was 87.3%, which is statistically significantly higher than the average result (47.9%) for other samples.

CONCLUSIONS

Correlations of the results of simple vestibulometric and audiometric tests allow us to recommend them to improve the diagnosis of idiopathic perilymphatic fistulas of the labyrinth windows. The possibilities of modern electrophysiological audiological research methods are subject to further study.

Keywords:

perilymphatic fistulas of the labyrinthine windows
audiological tests
predictive value of a positive result

Authors:

Egorov V.I.

Moscow Regional Clinical Research Institute named after M.F. Vladimirsky

Ryazantsev S.V.

Saint-Petersburg Research Institute of Ear, Throat, Nose and Speech

Kozarenko A.V.

Moscow Regional Scientific Research Clinical Institute MF Vladimirsky

Lilenko S.V.

Saint Petersburg ENT and Speech Research Institute;
North-Western State Medical University named after I.I. Mechnikov

Kozarenko M.A.

Saint-Petersburg Research Institute of Ear, Throat, Nose and Speech

Pol’schikova A.Yu.

Moscow Regional Scientific Research Clinical Institute MF Vladimirsky

Received:

15.06.2020

Accepted:

18.06.2021

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  2. Whitney T, Parnes S. Perilymph Fistulae: An Uncommon Cause of Dizziness. Global Journal of Otolaryngology. 2017;8(3):1-4.  https://doi.org/10.19080/gjo.2017.08.555738
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  13. Kozarenko MA. Diagnostics of non-inflammatory perilymphatic fistulas of labyrinth windows. Nauka i innovacii v medicine. 2018;9(1):55-58. (In Russ.).
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