The PGS with FISH-analysis on chromosomes 18, 21, X, Y was performed for patients with spermatozoa aneuploidies. PGS was carried out for 150 high quality embryos. The blastocyst formation rate was 54.00 %. 79.01 % of formatted blastocysts became from euploid embryos, 18.52 % of blastocysts became from aneuploid embryos and 2.47 % of blastocysts became from the embryos without nuclei in the investigated blastomeres. BFR was almost in 4.6 times higher (р<0,05) for the euploid embryos comparing with aneuploid embryos. Among the aneuploid embryos the BFR was in 6.5 times higher (р<0,05) for the embryos which had the aneuploidies of sexual chromosomes only comparing with embryos which had also the aneuploidies of the autosomes.