ЖурналыПодпискаАрхивКнигиПроектыО насРекламаДоставка/ОплатаКонтакты
+7 (495) 482-43-29
  • Главная
  • / Журналы
  • / Вернуться в журнал
  • / Содержание номера
  • / Статья
Есть мнение

Есть мнение

Авторы:
Марина Николаевна Носик,
Елизавета Петровна Быстрицкая,
Константин Александрович Рыжов,
Елена Викторовна Бережная,
Анна Витальевна Кузина,
Елизавета Павловна Костюченко,
Ольга Александровна Лобач,
Ирина Алексеевна Киселева,
Дмитрий Евгеньевич Киреев,
Ашхен Артаковна Тандилян,
Оксана Анатольевна Свитич

Журнал: Non nocere. Новый терапевтический журнал. 2026;(9):82-87.

Прочитано: 69 раз

Резюме

Влияние женских половых гормонов на экспрессию Toll-подобных рецепторов и репликацию ВИЧ-1.

Дата публикации: 13.10.2026

Литература / References
  1. Kawai T, Ikegawa M, Ori D, Akira S. Decoding Toll-like receptors: Recent insights and perspectives in innate immunity. Immunity. 2024;57(4):649-673. https://doi.org/10.1016/j.immuni.2024.03.004
  2. Carty M, Guy C, Bowie AG. Detection of Viral Infections by Innate Immunity. Biochem Pharmacol. 2021;183:114316. https://doi.org/10.1016/j.bcp.2020.114316
  3. Mekue LM, Nkenfou CN, Ngoufack MN, et al. Receptor 2 and 6 in the mother to child transmission of human immunodeficiency virus type-1. Biochem Mol Biol J. 2018;4(1):10. https://doi.org/10.21767/2471-8084.100059
  4. Lu W, Wang L, Xing J. Editorial: Antiviral innate immune sensing, regulation, and viral immune evasion. Front Immunol. 2024;14:1358542. https://doi.org/10.3389/fimmu.2023.1358542
  5. Heggelund L, Müller F, Lien E, et al. Increased expression of toll-like receptor 2 on monocytes in HIV infection: possible roles in inflammation and viral replication. Clin Infect Dis. 2004;39(2):264-269. https://doi.org/10.1086/421780
  6. Browne EP. The Role of Toll-Like Receptors in Retroviral Infection. Microorganisms. 2020;8(11):1787. https://doi.org/10.3390/microorganisms8111787
  7. Nguyen H, Gazy N, Venketaraman V. A Role of Intracellular Toll-Like Receptors (3, 7, and 9) in Response to Mycobacterium tuberculosis and Co-Infection with HIV. Int J Mol Sci. 2020;21(17):6148. https://doi.org/10.3390/ijms21176148
  8. Klein SL, Roberts CW. Sex and gender differences in infection and treatments for infectious diseases. Cham: Springer International Publishing; 2015. https://doi.org/10.1007/978-3-319-16438-0
  9. Nosik M, Ryzhov K, Rymanova I, et al. Dynamics of Plasmatic Levels of Pro- and Anti-Inflammatory Cytokines in HIV–Infected Individuals with M. tuberculosis Co-Infection. Microorganisms. 2021;9(11):2291. https://doi.org/10.3390/microorganisms9112291
  10. Shi Y, Ma J, Li S, et al. Sex difference in human diseases: mechanistic insights and clinical implications. Signal Transduct Target Ther. 2024;9(1):238. https://doi.org/10.1038/s41392-024-01929-7
  11. Addo MM, Altfeld M. Sex-based differences in HIV type 1 pathogenesis. J Infect Dis. 2014;209 Suppl 3(Suppl 3):S86-92. https://doi.org/10.1093/infdis/jiu175
  12. Rozman M, Zidovec-Lepej S, Jambrosic K, Babić M, Drmić Hofman I. Role of TLRs in HIV-1 Infection and Potential of TLR Agonists in HIV-1 Vaccine Development and Treatment Strategies. Pathogens. 2023; 12(1):92. https://doi.org/10.3390/pathogens12010092
  13. Donninelli G, Gessani S, Del Cornò M. Interplay between HIV-1 and Toll-like receptors in human myeloid cells: friend or foe in HIV-1 pathogenesis? J Leukoc Biol. 2016;99(1):97-105. https://doi.org/10.1189/jlb.4VMR0415-160R
  14. Hernández JC, Stevenson M, Latz E, Urcuqui-Inchima S. HIV type 1 infection up-regulates TLR2 and TLR4 expression and function in vivo and in vitro. AIDS Res Hum Retroviruses. 2012;28(10):1313-1328. https://doi.org/10.1089/aid.2011.0297
  15. Nosik M, Berezhnaya E, Bystritskaya E, et al. Female Sex Hormones Upregulate the Replication Activity of HIV-1 Sub-Subtype A6 and CRF02_AG but Not HIV-1 Subtype B. Pathogens. 2023;12(7):880. https://doi.org/10.3390/pathogens12070880
  16. Bolduc JF, Ouellet M, Hany L, Tremblay MJ. Toll-Like Receptor 2 Ligation Enhances HIV-1 Replication in Activated CCR6+ CD4+ T Cells by Increasing Virus Entry and Establishing a More Permissive Environment to Infection. J Virol. 2017;91(4):e01402-16. https://doi.org/10.1128/JVI.01402-16
  17. Del Cornò M, Cappon A, Donninelli G, Varano B, Marra F, Gessani S. HIV-1 gp120 signaling through TLR4 modulates innate immune activation in human macrophages and the biology of hepatic stellate cells. J Leukoc Biol. 2016;100(3):599-606. https://doi.org/10.1189/jlb.4A1215-534R
  18. Joshi A, Punke EB, Mehmetoglu-Gurbuz T, Peralta DP, Garg H. TLR9 polymorphism correlates with immune activation, CD4 decline and plasma IP10 levels in HIV patients. BMC Infect Dis. 2019;19(1):56. https://doi.org/10.1186/s12879-019-3697-9
  19. Vallejo A, Molina-Pinelo S, de Felipe B, et al. Brief Report: Toll-like Receptor 9-1635A/G Polymorphism Is Associated With HIV-1 Rebound After Four Weeks of Interruption of Antiretroviral Therapy. J Acquir Immune Defic Syndr. 2020;85(2):252-256. https://doi.org/10.1097/QAI.0000000000002437
  20. Panel on Antiretroviral Guidelines for Adults and Adolescents. Women With HIV. Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV. Department of Health and Human Services. Updated 12.09.2024. (date of access: August 10, 2026) https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-and-adolescent-arv/special-populations-women-hiv
  21. Panel on Antiretroviral Guidelines for Adults and Adolescents. Virologic Failure. Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents With HIV. Department of Health and Human Services. Updated 12.09.2024. (date of access: August 10, 2026) https://clinicalinfo.hiv.gov/en/guidelines/hiv-clinical-guidelines-adult-and-adolescent-arv/virologic-failure
slide-cover
slide-cover
slide-cover
slide-cover
slide-cover
slide-cover
Издательство «Медиа Сфера»
РекламаДоставка/ОплатаО насКонтактыОбучение для редакцийПолитика конфиденциальностиПолитика обработки персональных данныхПубличная оферта на реализацию издательской продукции
ЖурналыПодпискаАрхивКнигиПроекты
  • RuStore

© 1998-2026

  • Телефоны издательства:

  • +7 (495) 482-41-18
  • +7 (495) 482-43-29
  • Прямой телефон отдела подписки
    (только по вопросам заказов и доставки журналов)

  • +7 (800) 250-18-12
  • пн-пт с 10:00 до 18:00

  • Telegram
  • VK
info@mediasphera.ru
  • Почтовый адрес:

  • Издательство «Медиа Сфера»,
    а/я 54, Москва, Россия, 127238

  • RuStore

© 1998-2026