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Marushkin D.V.

Professor Larin's Phlebology Center

Larin S.I.

Professor Larin's Phlebology Center

Anti-aging neurology

Authors:

Marushkin D.V., Larin S.I.

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Journal: Non Nocere. New Therapeutic Journal. 2025;(12): 82‑87

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To cite this article:

Marushkin DV, Larin SI. Anti-aging neurology. Non Nocere. New Therapeutic Journal. 2025;(12):82‑87. (In Russ.)

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Abstract:

Cognitive health as a factor of national security.

Authors:

Marushkin D.V.

Professor Larin's Phlebology Center

Larin S.I.

Professor Larin's Phlebology Center

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References:

  1. World Health Organization. Ageing and health [Electronic resource] (Accessed: 12 November 2025). https://www.who.int/ru/news-room/fact-sheets/detail/ageing-and-health
  2. TASS. Ministry of Labor: a third of Russia’s population is over 55 [Electronic resource] (Accessed: 12 November 2025). https://tass.ru/obschestvo/2243023
  3. Government of the Russian Federation. Documents. Order of the Government of the Russian Federation dated 07.04.2025 No. 830-r “On approval of the Strategy of actions in the interests of senior citizens in the Russian Federation until 2030” [Electronic resource] (Accessed: 10 November 2025). https://government.ru/docs/54753/
  4. Tretyakova, V.D., Pultsina, K.I. Brain Aging: Key Theories and Neurophysiological Insights. Clinical Psychology and Special Education. 2024;13(4), 5-28. (In Russ.) https://doi.org/10.17759/cpse.2024130401
  5. Harman D. Aging: a theory based on free radical and radiation chemistry. J Gerontol. 1956 Jul;11(3):298-300.  https://doi.org/10.1093/geronj/11.3.298
  6. Singh R, Barden A, Mori T, Beilin L. Advanced glycation end-products: a review. Diabetologia. 2001 Feb;44(2):129-146.  https://doi.org/10.1007/s001250051591
  7. Heneka MT, Carson MJ, El Khoury J, et al. Neuroinflammation in Alzheimer’s disease. Lancet Neurol. 2015 Apr;14(4):388-405.  https://doi.org/10.1016/S1474-4422(15)70016-5
  8. Blackburn EH. Telomere states and cell fates. Nature. 2000 Nov 2;408(6808):53-56.  https://doi.org/10.1038/35040500
  9. Bratic A, Larsson NG. The role of mitochondria in aging. J Clin Invest. 2013 Mar;123(3):951-957.  https://doi.org/10.1172/JCI64125
  10. López-Otín C, Blasco MA, Partridge L, Serrano M, Kroemer G. The hallmarks of aging. Cell. 2013 Jun 6;153(6):1194-1217. https://doi.org/10.1016/j.cell.2013.05.039
  11. Vasenina EE, Levin OS, Sonin AG. Modern trends in epidemiology of dementia and management of patients with cognitive impairment. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(6-2):87-95. (In Russ.) https://doi.org/10.17116/jnevro20171176287-95
  12. Pyzhova O.V., Chasovskikh E.E. The problem of stigmatization of mental disorders in Russia. Innova. 2024;10(1):47-50. (In Russ.) https://doi.org/10.21626/innova/2024.1/04
  13. Wong KH, Anderson CD, Peterson C, et al. Rising Cognitive Disability as a Public Health Concern Among US Adults: Trends From the Behavioral Risk Factor Surveillance System, 2013-2023. Neurology. 2025 Oct 21;105(8): e214226. https://doi.org/10.1212/WNL.0000000000214226
  14. Elgina S.I., Bakhteeva A.V., Zueva S.A., et al. Dynamic assessment of the prevalence of cognitive impairment among young people. Medicine in Kuzbass. 2025;3:55-59.  https://doi.org/10.24412/2687-0053-2025-3-55-59
  15. Manwell LA, Tadros M, Ciccarelli TM, Eikelboom R. Digital dementia in the internet generation: excessive screen time during brain development will increase the risk of Alzheimer’s disease and related dementias in adulthood. J Integr Neurosci. 2022 Jan 28;21(1):28.  https://doi.org/10.31083/j.jin2101028
  16. Mattson MP, Longo VD, Harvie M. Impact of intermittent fasting on health and disease processes. Ageing Res Rev. 2017 Oct;39:46-58.  https://doi.org/10.1016/j.arr.2016.10.005
  17. Doma K, Ramachandran AK, Boullosa D, Connor J. The Paradoxical Effect of Creatine Monohydrate on Muscle Damage Markers: A Systematic Review and Meta-Analysis. Sports Med. 2022 Jul;52(7):1623-1645. https://doi.org/10.1007/s40279-022-01640-z
  18. Voronina TA, Litvinova SA, Gladysheva NA, Shulyndin AV. The known and new ideas about the mechanism of action and the spectrum of effects of Mexidol. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;125(5):22-33. (In Russ., In Engl.) https://doi.org/10.17116/jnevro202512505122
  19. Saxton RA, Sabatini DM. mTOR Signaling in Growth, Metabolism, and Disease. Cell. 2017 Mar 9;168(6):960-976.  https://doi.org/10.1016/j.cell.2017.02.004
  20. Ilyushchenko A.K., Matchekhina L.V., Tkacheva O.N., et al. Senolytic drugs: implications for clinical practice. Problems of Geroscience. 2023;(1):7-14. (In Russ.) https://doi.org/10.37586/2949-4745-1-2023-7-14
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