The quality of laboratory analytical results is determined by their reliability, timeliness and clinical informativity. To ensure these parameters at the proper level is necessary to implement management system in the laboratory quality, which is currently regulated by state standard GOST R ISO 15189. To facilitate the implementation of this standard can be used the online tool for the phased introduction quality in the laboratory, posted on the website of the World health organization. The lack of clearly defined national system of conformity GOST R ISO 15189 limits the application of the quality management system and can affect the results of laboratory tests. The development of alternative system of accreditation of medical laboratories according to GOST R ISO 15189 laboratory by professional community will improve the quality of laboratory testing and medical care in general.