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Aleksandrov Yu.K.

Yaroslavl State Medical University

Semikov V.I.

Sechenov First Moscow State Medical University (Sechenov University)

Shulutko A.M.

Sechenov First Moscow State Medical University (Sechenov University)

Non-functioning parathyroid cysts

Authors:

Aleksandrov Yu.K., Semikov V.I., Shulutko A.M.

More about the authors

Journal: Pirogov Russian Journal of Surgery. 2024;(2): 68‑74

DOI: 10.17116/hirurgia202402168

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Table of contents

NON-FUNCTIONING PARATHYROID CYSTS
NON-FUNCTIONING PARATHYROID CYSTS

To cite this article:

Aleksandrov YuK, Semikov VI, Shulutko AM. Non-functioning parathyroid cysts. Pirogov Russian Journal of Surgery. 2024;(2):68‑74. (In Russ.)
https://doi.org/10.17116/hirurgia202402168

Подписка 2025-2 (Pirogov Russian Journal of Surgery)
МСФ на ЯМ
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OBJECTIVE

To study the features of clinical course, diagnosis and treatment of true non-functioning parathyroid cysts.

MATERIAL AND METHODS

We retrospectively analyzed 18 patients with non-functioning true parathyroid cysts. Inclusion criteria: US-confirmed anechoic lesion of the neck without tissue component, cytological data on cystic lesion, high cystic parathyroid hormone and no laboratory signs of hyperparathyroidism.

RESULTS

Non-functioning parathyroid cysts were asymptomatic and diagnosed accidentally after ultrasound of the neck. All patients were women aged 35—77 years. Four patients had cysts near the upper parathyroid glands, 14 patients — near the lower parathyroid glands. Of these, 2 ones had cysts below the level of the clavicle. Cyst volume was 4.3—110.3 cm3 (24.1±26.2 cm3). High cystic parathyroid hormone (2012.5±946.7 pg/ml) was observed in all patients. Simple aspiration was performed in 5 patients, aspiration with sclerotherapy — in 10 patients, cystectomy — in 3 patients. Recurrence was diagnosed in 1 patient after aspiration and 2 patients after sclerotherapy.

CONCLUSION

No pathognomonic clinical and ultrasonic symptoms, as well as specific cytological data lead to misdiagnosis. Analysis of PTH in non-functioning parathyroid cysts is essential for diagnosis. Minimally invasive treatment is preferable for true parathyroid cysts. However, these approaches are not radical.

Keywords:

parathyroid gland
cyst
parathyroid hormone
minimally invasive treatment

Authors:

Aleksandrov Yu.K.

Yaroslavl State Medical University

Semikov V.I.

Sechenov First Moscow State Medical University (Sechenov University)

Shulutko A.M.

Sechenov First Moscow State Medical University (Sechenov University)

Received:

03.04.2023

Accepted:

29.04.2023

List of references:

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