The treatment results of 109 patients with the disseminated septic peritonitis were analyzed. All patients were divided in two statistically similar groups. The first group of patients was treated using the standart approach (open surgery, eliminating the cause of peritonitis followed by further endoscopic planned sanations of the abdominal cavity). Difference of the treatment approach among the patients of the second group (n=41) was in using the pulsing stream of anticeptic for fibrine onlays elimination and the use of 200 ml of immobilized form of sodium hypochlorite gel for the final sanation. The treatment results among these patients were significantly better (the endotoxicosis parameters were 1.5 times lower and the recovery of motor intestinal function was 2 times faster). The morbidity level was 9% lower and the lethality level was 4% lower in comparison with patients of the 1st group.