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Ivanov V.A.

Petrovsky National Research Center of Surgery, Moscow, Russia

Evseev E.P.

Petrovsky National Research Center of Surgery, Moscow, Russia

Ivanova E.V.

Petrovsky National Research Center of Surgery, Moscow, Russia

Ivanova L.N.

Petrovsky National Research Center of Surgery, Moscow, Russia

Nikityuk T.G.

Petrovsky National Research Center of Surgery, Moscow, Russia

Fomin M.A.

Petrovsky National Research Center of Surgery, Moscow, Russia

Aidamirov Ya.A.

Petrovsky National Research Center of Surgery, Moscow, Russia

Balakin E.V.

Petrovsky National Research Center of Surgery, Moscow, Russia

Severe aortic stenosis in surgery of acquired heart disease: long-term results

Authors:

Ivanov V.A., Evseev E.P., Ivanova E.V., Ivanova L.N., Nikityuk T.G., Fomin M.A., Aidamirov Ya.A., Balakin E.V.

More about the authors

Journal: Russian Journal of Cardiology and Cardiovascular Surgery. 2026;19(2): 35‑41

DOI: 10.17116/kardio20261902135

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Table of contents

SEVERE AORTIC STENOSIS IN SURGERY OF ACQUIRED HEART DISEASE: LONG-TERM RESULTS
SEVERE AORTIC STENOSIS IN SURGERY OF ACQUIRED HEART DISEASE: LONG-TERM RESULTS

To cite this article:

Ivanov VA, Evseev EP, Ivanova EV, et al. Severe aortic stenosis in surgery of acquired heart disease: long-term results. Russian Journal of Cardiology and Cardiovascular Surgery. 2026;19(2):35‑41. (In Russ.)
https://doi.org/10.17116/kardio20261902135

Подписка 2026 Кардиология и сердечно-сосудистая хирургия (Russian Journal of Cardiology and Cardiovascular Surgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
Abstract:

OBJECTIVE

To evaluate long-term survival, physical activity, hemodynamic parameters on aortic prosthesis and cardiac remodeling after surgical treatment of severe aortic stenosis.

MATERIAL AND METHODS

In 2019, we retrospectively analyzed the results of 100 consecutive surgeries in patients with critical aortic stenosis. Appropriate surgical intervention, anesthesia, perfusion and intensive care reduced in-hospital mortality and morbidity in these patients. Ninety-eight patients were discharged.

RESULTS

The follow-up period was 7.8 (range 6.3—10.0) years. In long-term period, 6 patients died, and 10-year Kaplan-Meier survival rate was 94%. There were no redo surgeries. Dysfunction of aortic prosthesis was observed in one patient due to pannus. Twenty-five (29%) patients were assigned to functional class I, 59 (69%) — class II, and only 2 (2%) patients were assigned to class III. According to transthoracic echocardiography, maximum and mean pressure gradients were 30.5±14.1 and 16.6±9.6 mm Hg, respectively. Regression of myocardial mass and myocardial mass index was 22% and 23% compared to early postoperative data, respectively.

CONCLUSION

In patients with severe aortic stenosis and extremely unfavorable clinical prognosis, surgical treatment remains the main method. Normalization of intracardiac hemodynamics leads to significant reverse cardiac remodeling and improves QoL and life expectancy.

Keywords:

severe aortic valve stenosis
surgical replacement of aortic valve
regression of left ventricular myocardial hypertrophy
mechanical and biological prostheses

Authors:

Ivanov V.A.

Petrovsky National Research Center of Surgery, Moscow, Russia

Evseev E.P.

Petrovsky National Research Center of Surgery, Moscow, Russia

Ivanova E.V.

Petrovsky National Research Center of Surgery, Moscow, Russia

Ivanova L.N.

Petrovsky National Research Center of Surgery, Moscow, Russia

Nikityuk T.G.

Petrovsky National Research Center of Surgery, Moscow, Russia

Fomin M.A.

Petrovsky National Research Center of Surgery, Moscow, Russia

Aidamirov Ya.A.

Petrovsky National Research Center of Surgery, Moscow, Russia

Balakin E.V.

Petrovsky National Research Center of Surgery, Moscow, Russia

Received:

26.12.2024

Accepted:

12.05.2025

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References:

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