Abstract Objective — to present the results of staged replacement of the entire aorta in patients with widespread aneurysmal dilatation of the aorta. Material and methods. There were 24 procedures of staged aortic replacement for the period from May 2015 to December 2018 at the department of aortic surgery. The study included patients with ascending aortic, aortic arch and thoracoabdominal aortic aneurysm undergoing elective staged replacement of the entire aorta. Nineteen patients underwent antegrade aortic replacement (from the aortic root to the bifurcation) and five patients – retrograde aortic repair. Antegrade aortic replacement implied proximal repair followed by distal aortic reconstruction. Ascending aorta and aortic arch replacement was performed under hypothermic circulatory arrest and antegrade cerebral perfusion. In all cases, aortic arch prosthesis was invaginated within 6—7 cm into the descending thoracic aorta. Thoracoabdominal aorta replacement was associated with normothermic cardiopulmonary bypass and selective visceral perfusion. Results. Intraoperative, in-hospital and 30-day mortality was absent after both stages of retrograde aortic replacement. In-hospital mortality after the second stage of antegrade aortic replacement was 5% (n=1). The interval between operations was 7.1±2.3 months. There was no mortality within follow-up. CT-signs of contrast agent leakage were not observed in all patients. In one case, left renal artery stenosis was detected. Conclusion. A personalized approach is essential in patients with widespread aortic aneurysmal disease to determine optimal surgical strategy. Staged replacement of the aorta is associated with satisfactory immediate results.