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Nizolin D.V.

Almazov National Medical Research Center

Fedorov E.V.

Almazov National Medical Research Center

Kim A.V.

Almazov National Medical Research Center

Mitrofanova L.B.

Almazov National Medical Research Center

Khachatryan V.A.

Almazov National Medical Research Center

Combination of tumors of different histogenesis in pediatric neurosurgery

Authors:

Nizolin D.V., Fedorov E.V., Kim A.V., Mitrofanova L.B., Khachatryan V.A.

More about the authors

Journal: Burdenko's Journal of Neurosurgery. 2021;85(2): 80‑90

DOI: 10.17116/neiro20218502180

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Table of contents

COMBINATION OF TUMORS OF DIFFERENT HISTOGENESIS IN PEDIATRIC NEUROSURGERY
COMBINATION OF TUMORS OF DIFFERENT HISTOGENESIS IN PEDIATRIC NEUROSURGERY

To cite this article:

Nizolin DV, Fedorov EV, Kim AV, Mitrofanova LB, Khachatryan VA. Combination of tumors of different histogenesis in pediatric neurosurgery. Burdenko's Journal of Neurosurgery. 2021;85(2):80‑90. (In Russ., In Engl.)
https://doi.org/10.17116/neiro20218502180

Подписка 2025 Журнал «Вопросы нейрохирургии» имени Н.Н. Бурденко (Burdenko's Journal of Neurosurgery)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

Multiple gliomas are determined by synchronous two or more tumors located in different brain regions. It is important to distinguish multiple primary tumors and metastatic brain lesion. In the first case, tumor spread can`t be explained by dissemination along the cerebrospinal fluid pathways, commissural fibers or local metastases. Multiple primary tumors with different histological structures are called bidermal neoplasms. Surgery is preferred in these patients with severe symptoms. The purpose of surgery is maximum resection of tumor. Follow-up may be advisable for small tumors without clinical manifestations. Treatment of multiple gliomas includes surgery, radiotherapy and chemotherapy. Multiple tumor process in children is much more severe compared to a single neoplasia that requires neurological and neuroimaging control and determines treatment strategy. The authors report 3 children with multicentric gliomas, discuss the various aspects of diagnosis and treatment of multiple gliomas and formulate the recommendations for the treatment based on own clinical experience and literature data.

Keywords:

multiple tumors
multicentric gliomas
pediatric neurooncology

Authors:

Nizolin D.V.

Almazov National Medical Research Center

Fedorov E.V.

Almazov National Medical Research Center

Kim A.V.

Almazov National Medical Research Center

Mitrofanova L.B.

Almazov National Medical Research Center

Khachatryan V.A.

Almazov National Medical Research Center

Received:

29.11.2020

Accepted:

05.02.2021

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