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Parfenov A.I.

GBUZ "Moskovskiĭ klinicheskiĭ nauchno-prakticheskiĭ tsentr" Departamenta zdravookhraneniia Moskvy

Krums L.M.

Moskovskiĭ klinicheskiĭ nauchno-prakticheskiĭ tsentr

Protein-losing enteropathy

Authors:

Parfenov A.I., Krums L.M.

More about the authors

Journal: Therapeutic Archive. 2017;89(2): 4‑9

DOI: 10.17116/terarkh20178924-9

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Table of contents

PROTEIN-LOSING ENTEROPATHY
PROTEIN-LOSING ENTEROPATHY

To cite this article:

Parfenov AI, Krums LM. Protein-losing enteropathy. Therapeutic Archive. 2017;89(2):4‑9. (In Russ.)
https://doi.org/10.17116/terarkh20178924-9

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Abstract:

Protein-losing enteropathy (PLE) is a rare complication of intestinal diseases. Its main manifestation is hypoproteinemic edema. The diagnosis of PLE is based on the verification of protein loss into the intestinal lumen, by determining fecal α1-antitrypsin concentration and clearance. The localization of the affected colonic segment is clarified using radiologic and endoscopic techniques. The mainstay of treatment for PLE is a fat-free diet enriched with medium-chain triglycerides. Surgical resection of the affected segment of the colon may be the treatment of choice for severe hypoproteinemia resistant to drug therapy.

Keywords:

protein-losing enteropathy
intestinal lymphangiectasia
hypoproteinemia
hypoalbuminemia
α1-antitrypsin
fat-free diet
medium-chain triglycerides

Authors:

Parfenov A.I.

GBUZ "Moskovskiĭ klinicheskiĭ nauchno-prakticheskiĭ tsentr" Departamenta zdravookhraneniia Moskvy

Krums L.M.

Moskovskiĭ klinicheskiĭ nauchno-prakticheskiĭ tsentr

Close metadata

References:

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