Morphological markers of liver function in alcohol intoxication

Morozov Iu.E.; Porodenko V.A.; Travenko E.N.; Gornostaev D.V.

doi:https://doi.org/10.17116/sudmed20196203137

Morozov Iu.E.

Baltiĭskiĭ federal'nyĭ universitet im. Immanuila Kanta, Kaliningrad

Porodenko V.A.

Kuban State Medical University, Ministry of Health of the Russia, Krasnodar, Russia, 350063

Travenko E.N.

Kuban State Medical University, Ministry of Health of the Russia, Krasnodar, Russia, 350063

Gornostaev D.V.

Biuro sudebno-meditsinskoĭ ékspertizy Departamenta zdravookhraneniia Moskvy

Morphological markers of liver function in alcohol intoxication

Authors:

Morozov Iu.E., Porodenko V.A., Travenko E.N., Gornostaev D.V.

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Journal: Forensic Medical Expertise. 2019;62(3): 37‑41

DOI: 10.17116/sudmed20196203137

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Morozov IuE, Porodenko VA, Travenko EN, Gornostaev DV. Morphological markers of liver function in alcohol intoxication. Forensic Medical Expertise. 2019;62(3):37‑41. (In Russ.)
https://doi.org/10.17116/sudmed20196203137

Подписка 2026 Судебно-медицинская экспертиза (Forensic Medical Expertise)

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Abstract:

The aim of this study was to find additional diagnostic markers characterizing the functional state of the liver to substantiate the cause of death from ethanol poisoning. A total of 95 deaths from acute ethanol poisoning and 15 deaths from craniocerebral injury were studied. Signs of steatosis, chronic hepatitis or cirrhosis were taken into account in histological examination of the liver. The histochemical activity of ethano-locking enzymes was determined in structurally functional zones of the acini: portal pathways (Zone 1), liver beams (Zone 2) and central veins (Zone 3). Quantitative indices characterizing functional-metabolic activity of the liver during acute ethanol poisoning were obtained.

Keywords:

ethanol poisoning

destructive changes of the liver

ethano-locking enzymes

functional zones of liver acini

Authors:

Morozov Iu.E.

Baltiĭskiĭ federal'nyĭ universitet im. Immanuila Kanta, Kaliningrad

Porodenko V.A.

Kuban State Medical University, Ministry of Health of the Russia, Krasnodar, Russia, 350063

Travenko E.N.

Kuban State Medical University, Ministry of Health of the Russia, Krasnodar, Russia, 350063

Gornostaev D.V.

Biuro sudebno-meditsinskoĭ ékspertizy Departamenta zdravookhraneniia Moskvy

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References:

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