The strength and the energy of a striking blow with a clenched fist may be as high as 300 kgf (3,000 H) and 824.4 J respectively. Pressing a human body against a hard surface leads to a deep chest deflection while the rupture of the liver is associated with a lower blow strength and energy (2,000 H and 141.5 J respectively). In such situations, the shockproof mechanisms of the injury prevail giving rise to antishock peripheral and central ruptures of the liver due to the general deformation and displacement of this organ in the direction of the blow. In the absence of barriers preventing the inertial movement of the body, even a strong strike (1950 H) with an energy of 202.5 J does not cause a damage to the liver; it occurs when the strike strength and energy amount to 2650 H and 260.1 J respectively. In such cases, the direct injury mechanism develops manifested in the formation of local liver injures. The results of the study suggest the possibility of the rupture of the liver inflicted by a clenched fist strike delivered to the abdomen.