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Внутренние дела

Внутренние дела

Авторы:
Белоусов А.С.,
Стуров Н.В.

Журнал: Non nocere. Новый терапевтический журнал. 2025;(10):38-44.

Прочитано: 478 раз

Резюме

Кишечная микробиота и ее влияние на инфекционные проявления ХОБЛ (обострения, пневмонии).

Дата публикации: 18.11.2025

Литература / References
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  2. Global Initiative for Chronic Obstructive Lung Disease (GOLD). Global Strategy for the Diagnosis, Management, and Prevention of Chronic Obstructive Pulmonary Disease (2024 Report) (Date of Access: 15.08.2025). https://goldcopd.org/2024-gold-report/
  3. Li N, Dai Z, Wang Z, et al. Gut microbiota dysbiosis contributes to the development of chronic obstructive pulmonary disease. Respir Res. 2021 Oct 25;22(1):274. https://doi.org/10.1186/s12931-021-01872-z
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  6. Budden KF, Gellatly SL, Wood DL, et al. Emerging pathogenic links between microbiota and the gut-lung axis. Nat Rev Microbiol. 2017 Jan;15(1):55-63. https://doi.org/10.1038/nrmicro.2016.142
  7. Chakradhar S. A curious connection: Teasing apart the link between gut microbes and lung disease. Nat Med. 2017 Apr 7;23(4):402-404. https://doi.org/10.1038/nm0417-402
  8. Wang L, Cai Y, Garssen J, Henricks PAJ, Folkerts G, Braber S. The Bidirectional Gut-Lung Axis in Chronic Obstructive Pulmonary Disease. Am J RespirCrit Care Med. 2023 May 1;207(9):1145-1160. https://doi.org/10.1164/rccm.202206-1066TR
  9. Gibson GR, Hutkins R, Sanders ME, et al. Expert consensus document: The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of prebiotics. Nat Rev GastroenterolHepatol. 2017 Aug;14(8):491-502. https://doi.org/10.1038/nrgastro.2017.75
  10. Brassard P, Vutcovici M, Ernst P, et al. Increased incidence of inflammatory bowel disease in Québec residents with airway diseases. EurRespir J. 2015 Apr;45(4):962-928. https://doi.org/10.1183/09031936.00079414
  11. Raftery AL, Tsantikos E, Harris NL, Hibbs ML. Links Between Inflammatory Bowel Disease and Chronic Obstructive Pulmonary Disease. Front Immunol. 2020 Sep 11;11:2144. https://doi.org/10.3389/fimmu.2020.02144
  12. Berkowitz L, Schultz BM, Salazar GA, et al. Impact of Cigarette Smoking on the Gastrointestinal Tract Inflammation: Opposing Effects in Crohn’s Disease and Ulcerative Colitis. Front Immunol. 2018 Jan 30;9:74. https://doi.org/10.3389/fimmu.2018.00074
  13. Garrow D, Delegge MH. Risk factors for gastrointestinal ulcer disease in the US population. Dig Dis Sci. 2010 Jan;55(1):66-72. https://doi.org/10.1007/s10620-008-0708-x
  14. Ahn SV, Lee E, Park B, et al. Cancer development in patients with COPD: a retrospective analysis of the National Health Insurance Service-National Sample Cohort in Korea. BMC Pulm Med. 2020 Jun 15;20(1):170. https://doi.org/10.1186/s12890-020-01194-8
  15. Kim J, Lee JH, Kim Y, et al. Association between chronic obstructive pulmonary disease and gastroesophageal reflux disease: a national cross-sectional cohort study. BMC Pulm Med. 2013 Aug 9;13:51. https://doi.org/10.1186/1471-2466-13-51
  16. Gomes-Filho IS, Cruz SSD, Trindade SC, et al. Periodontitis and respiratory diseases: A systematic review with meta-analysis. Oral Dis. 2020 Mar;26(2):439-446. https://doi.org/10.1111/odi.13228
  17. Lochhead P, Khalili H, Ananthakrishnan AN, Richter JM, Chan AT. Association Between Circulating Levels of C-Reactive Protein and Interleukin-6 and Risk of Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2016 Jun;14(6):818-824.e6. https://doi.org/10.1016/j.cgh.2016.01.016
  18. Matera MG, Calzetta L, Cazzola M. TNF-alpha inhibitors in asthma and COPD: we must not throw the baby out with the bath water. Pulm Pharmacol Ther. 2010 Apr;23(2):121-128. https://doi.org/10.1016/j.pupt.2009.10.007
  19. Pugliese D, Felice C, Papa A, et al. Anti TNF-α therapy for ulcerative colitis: current status and prospects for the future. Expert Rev ClinImmunol. 2017 Mar;13(3):223-233. https://doi.org/10.1080/1744666X.2017.1243468
  20. Barnes PJ. Unexpected failure of anti-tumor necrosis factor therapy in chronic obstructive pulmonary disease. Am J RespirCrit Care Med. 2007 May 1;175(9):866-867. https://doi.org/10.1164/rccm.200702-253ED
  21. Nagaraju GP, Bramhachari PV, Raghu G, El-Rayes BF. Hypoxia inducible factor-1α: Its role in colorectal carcinogenesis and metastasis. Cancer Lett. 2015 Sep 28;366(1):11-18. https://doi.org/10.1016/j.canlet.2015.06.005
  22. Ramsheh MY, Haldar K, Esteve-Codina A, et al. Lung microbiome composition and bronchial epithelial gene expression in patients with COPD versus healthy individuals: a bacterial 16S rRNA gene sequencing and host transcriptomic analysis. Lancet Microbe. 2021 Jul;2(7): e300-e310. https://doi.org/10.1016/S2666-5247(21)00035-5
  23. Madapoosi SS, Cruickshank-Quinn C, Opron K, et al. Lung Microbiota and Metabolites Collectively Associate with Clinical Outcomes in Milder Stage Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2022 Aug 15;206(4):427-439. https://doi.org/10.1164/rccm.202110-2241OC
  24. Parada Venegas D, De la Fuente MK, Landskron G, et al. Short Chain Fatty Acids (SCFAs)-Mediated Gut Epithelial and Immune Regulation and Its Relevance for Inflammatory Bowel Diseases. Front Immunol. 2019 Mar 11;10:277. https://doi.org/10.3389/fimmu.2019.00277
  25. Young RP, Hopkins RJ, Marsland B. The Gut-Liver-Lung Axis. Modulation of the Innate Immune Response and Its Possible Role in Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2016 Feb;54(2):161-169. https://doi.org/10.1165/rcmb.2015-0250PS
  26. Freedman SB, Schnadower D, Tarr PI. The Probiotic Conundrum: Regulatory Confusion, Conflicting Studies, and Safety Concerns. JAMA. 2020 Mar 3;323(9):823-824. https://doi.org/10.1001/jama.2019.22268
  27. Mindt BC, DiGiandomenico A. Microbiome Modulation as a Novel Strategy to Treat and Prevent Respiratory Infections. Antibiotics. 2022;11(4):474. https://doi.org/10.3390/antibiotics11040474
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