Experience of surgical treatment of 111 patients with thoracoabdominal aorta aneurysm are presented in the article. All patients were operated in terms 2007 to December 2011 in the department of aortic surgery of acad. B.V. Petrovskogo RSCS of RAMS. All patients were divided into 3 groups. Thoracoabdominal aorta prosthetics from isthmus to bifurcation was performed in 10 patients of the first group. It was done descending thoracic aorta prosthetics in the second group (72 patients). The third group (29 patients) had suprarenal aorta prosthetics. The groups were comparable with respect to initial severity of underlying and concomitant diseases. Hemorrhage was 6242±3040, 2666±1590 and 2962±1547 ml respectively. Liver and renal failure developed in 10, 7 and 24% of cases respectively (p<0.05). Respiratory failure developed in 40, 33 and 27.6% of cases. Mortality was 10, 7 and 13.8% respectively. It was concluded about comparable treatment outcomes regardless of the amount of reconstruction. It is necessary to develop the techniques improving surgical treatment results and decreasing postoperative complications frequency.