Renal urothelial carcinoma mainly composed of signet-ring cells

Guseva E.A.

Saint Petersburg Bureau of Forensic Medical Examination

Konstantinova A.M.

Federal State Budgetary Educational Institution of Higher Professional Education «St. Petersburg State University», St. Petersburg, Russia;
The State Budgetary Healthcare Institution «Clinical research and practical center for specialized oncological care», St. Petersburg, Russia;
Private educational institution of higher education «Saint-Petersburg Medico-Social Institute», St. Petersburg, Russia

Shelekhova K.V.

The State Budgetary Healthcare Institution «Clinical research and practical center for specialized oncological care», St. Petersburg, Russia;
Private educational institution of higher education «Saint-Petersburg Medico-Social Institute», St. Petersburg, Russia

Renal urothelial carcinoma mainly composed of signet-ring cells

Authors:

Guseva E.A., Konstantinova A.M., Shelekhova K.V.

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Journal: Russian Journal of Archive of Pathology. 2015;77(6): 50‑53

DOI: 10.17116/patol201577650-53

Downloaded: 53

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To cite this article:

Guseva EA, Konstantinova AM, Shelekhova KV. Renal urothelial carcinoma mainly composed of signet-ring cells. Russian Journal of Archive of Pathology. 2015;77(6):50‑53. (In Russ.)
https://doi.org/10.17116/patol201577650-53

Подписка 2025 (Russian Journal of Archive of Pathology)

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Autopsy study of an 80-year-old man has identified his renal tumor metastasizing to the heart, lung, and liver as urothelial carcinoma; at the same time some cells in the main tumor and all cells in the metastases had a signet-ring phenotype, but neither mucicarcimine nor alcian blue stained the cell cytoplasm. The paper provides the histological and immunohistochemical pattern of the tumor and emphasizes its exclusive rarity. Attention is drawn to the possibility of signet-ring cell transformation in the cells of different tumors, including nonepithelial ones.

Keywords:

renal urothelial carcinoma