Talc-induced pulmonary granulomas in drug addicts

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Latartseva L.N.

Donetskoe oblastnoe biuro sudebno-meditsinskoĭ ékspertizy

Krivenko A.N.

Otdelenie patologii, Gospital' Dzhonsa Khopkinsa, Baltimor, Mérilend, SShA

Talc-induced pulmonary granulomas in drug addicts

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Latartseva L.N., Krivenko A.N.

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Journal: Russian Journal of Archive of Pathology. 2013;75(4): 24‑27

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To cite this article:

Latartseva LN, Krivenko AN. Talc-induced pulmonary granulomas in drug addicts. Russian Journal of Archive of Pathology. 2013;75(4):24‑27. (In Russ.)

Подписка 2025 (Russian Journal of Archive of Pathology)

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Among the diseases accompanied by granuloma formation in the lung, there is so-called granulomatosis developing in injection drug users who have been long injecting suspensions of oral medications containing talc and other water insoluble fillers. 102 deaths of chronic intravenous drug users were examined; 12 of whom showed pulmonary talc-induced granulomatosis. Their morphology was studied using polarized light microscopy. The main mechanisms of thanatogenesis in lethal cases within the first hours after intravenous injection of talc-containing oral medication suspensions are explained.

Keywords:

pulmonary granulomatosis

intravenous drug abuse

talc

polarized light microscopy

Authors:

Latartseva L.N.

Donetskoe oblastnoe biuro sudebno-meditsinskoĭ ékspertizy

Krivenko A.N.

Otdelenie patologii, Gospital' Dzhonsa Khopkinsa, Baltimor, Mérilend, SShA

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