Retrolental amyloidosis of the vitreous body (case study)

V.A. Shaimova

Academy of Postgraduate Education of the Federal Scientific and Clinical Center for Specialized Medical Assistance and Medical Technologies of the Federal Medical Biological Agency;
OOO Centr Zreniya

ORCID: 0000-0001-5586-5042

Yu.V. Nosul

Center Zreniya LLC;
Municipal Clinical Hospital No. 6

S.Kh. Kuchkildina

OOO Centr Zreniya

ORCID: 0000-0003-4760-1391

A.N. Kulikov

S.M. Kirov Military Medical Academy

SPIN RSCI: 6440-7706
Scopus AuthorID: 57001225300
ResearcherID: M-2094-2016
ORCID: 0000-0002-5274-6993

D.S. Maltsev

S.M. Kirov Military Medical Academy

SPIN RSCI: 4903-2333
Scopus AuthorID: 37091094500
ORCID: 0000-0001-6598-3982

T.B. Shaimov

OOO Centr Zreniya

ORCID: 0000-0002-7020-5349

R.B. Shaimov

OOO Centr Zreniya

ORCID: 0000-0002-9123-2354

E.S. Golovneva

Multidisciplinary Center of Laser Medicine;
South Ural State Medical University

T.G. Kravchenko

Multiprofile Center for Laser Medicine

ORCID: 0000-0002-9351-9789

A.Yu. Kholopova

Chelyabinsk Regional Pathoanatomical Bureau

V.V. Ermilov

Volgograd State Medical University

R.B. Berdnikov

Ural State Medical University;
Ural Scientific Research Institute of Phthisiopulmonology — branch of National Research Medical Center of Phthisiopulmonology and Infectious Diseases

Retrolental amyloidosis of the vitreous body (case study)

Authors:

V.A. Shaimova, Yu.V. Nosul, S.Kh. Kuchkildina, A.N. Kulikov, D.S. Maltsev, T.B. Shaimov, R.B. Shaimov, E.S. Golovneva, T.G. Kravchenko, A.Yu. Kholopova, V.V. Ermilov, R.B. Berdnikov

More about the authors

Journal: Russian Annals of Ophthalmology. 2021;137(4): 98‑103

DOI: 10.17116/oftalma202113704198

Downloaded: 92

To cite this article:

Shaimova VA, Nosul YuV, Kuchkildina SKh, Kulikov AN, Maltsev DS, Shaimov TB, Shaimov RB, Golovneva ES, Kravchenko TG, Kholopova AYu, Ermilov VV, Berdnikov RB. Retrolental amyloidosis of the vitreous body (case study). Russian Annals of Ophthalmology. 2021;137(4):98‑103. (In Russ., In Engl.)
https://doi.org/10.17116/oftalma202113704198

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Accumulations of pathological amyloid protein in the vitreous can be a pathognomonic morphological sign of systemic amyloidosis, which is characterized by deposition of insoluble fibrillar protein aggregates (amyloid) in various organs and tissues. The article describes a clinical case of a female 65-year-old patient with bilateral vitreous floaters and histologically confirmed vitreous amyloidosis on the right eye. The patient had undergone YAG laser vitreolysis of the right eye 3 years ago on the Ultra Q Reflex system («Ellex», Australia) to treat an atypical Weiss ring. Diagnosis of vitreous amyloidosis was confirmed using the following equipment: video slit lamp SL9900 («CSO», Italy), optical coherence tomography system Solix («Optovue», USA), B-scan Plus («Accutome», USA), microscope CX41RF («Olympus Corporation», Japan). Due to significant visual deterioration in the right eye, the patient underwent vitrectomy. Microscopic examination of the surgical sample showed the presence of amyloid deposits revealed by the brick-red specific staining with congo red dye and apple-green birefringence of the stained areas in polarized light.

Keywords:

vitreous floaters

vitreous amyloidosis

YAG laser vitreolysis

Authors:

V.A. Shaimova

Academy of Postgraduate Education of the Federal Scientific and Clinical Center for Specialized Medical Assistance and Medical Technologies of the Federal Medical Biological Agency;
OOO Centr Zreniya

ORCID: 0000-0001-5586-5042

Yu.V. Nosul

Center Zreniya LLC;
Municipal Clinical Hospital No. 6

S.Kh. Kuchkildina

OOO Centr Zreniya

ORCID: 0000-0003-4760-1391

A.N. Kulikov

S.M. Kirov Military Medical Academy

SPIN RSCI: 6440-7706
Scopus AuthorID: 57001225300
ResearcherID: M-2094-2016
ORCID: 0000-0002-5274-6993

D.S. Maltsev

S.M. Kirov Military Medical Academy

SPIN RSCI: 4903-2333
Scopus AuthorID: 37091094500
ORCID: 0000-0001-6598-3982

T.B. Shaimov

OOO Centr Zreniya

ORCID: 0000-0002-7020-5349

R.B. Shaimov

OOO Centr Zreniya

ORCID: 0000-0002-9123-2354

E.S. Golovneva

Multidisciplinary Center of Laser Medicine;
South Ural State Medical University

T.G. Kravchenko

Multiprofile Center for Laser Medicine

ORCID: 0000-0002-9351-9789

A.Yu. Kholopova

Chelyabinsk Regional Pathoanatomical Bureau

V.V. Ermilov

Volgograd State Medical University

R.B. Berdnikov

Ural State Medical University;
Ural Scientific Research Institute of Phthisiopulmonology — branch of National Research Medical Center of Phthisiopulmonology and Infectious Diseases

Received:

09.07.2021

Accepted:

17.07.2021

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