Biointegration properties of eyelid weight implants made of various materials (experimental study)

Y.O. Grusha

I.M. Sechenov First Moscow State Medical University (Sechenov University);
Krasnov Research Institute of Eye Diseases

ORCID: 0000-0002-6461-8243

A.A. Fedorov

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

ORCID: 0000-0003-2590-5087

V.A. Sheptulin

Research Institute of Eye Diseases

E.I. Fettser

Krasnov Research Institute of Eye Diseases;
Sechenov First Moscow State Medical University

ORCID: 0000-0002-3729-7480

Biointegration properties of eyelid weight implants made of various materials (experimental study)

Authors:

Y.O. Grusha, A.A. Fedorov, V.A. Sheptulin, E.I. Fettser

More about the authors

Journal: Russian Annals of Ophthalmology. 2020;136(6): 19‑25

DOI: 10.17116/oftalma202013606119

Downloaded: 29

To cite this article:

Grusha YO, Fedorov AA, Sheptulin VA, Fettser EI. Biointegration properties of eyelid weight implants made of various materials (experimental study). Russian Annals of Ophthalmology. 2020;136(6):19‑25. (In Russ., In Engl.)
https://doi.org/10.17116/oftalma202013606119

Доказательная гастроэнтерология: pro et contra

Актуальные вопросы педиатрической практики

Использование инфографики авторами научных работ

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PURPOSE

To investigate biointegration properties of implants made of gold, platinum and platinum-gold alloy.

MATERIAL AND METHODS

The study enrolled 4 Chinchilla rabbits (8 eyelids). Palpebral implants manufactured of gold, platinum and platinum-gold alloy were placed into the eyelids of the experimental animals. The morphological examination was performed 1 and 6 months after the implantation using paraffin sections.

RESULTS

Light microscopy revealed that the implant beds were surrounded by pronounced fibrovascular capsule of uneven thickness over the whole follow-up. The capsule formed after the placement of an implant made of gold and platinum alloy was more loose. However, the emerging connective tissue bridges of the capsule contributed to its immobilization in the tissues and lower risk of extrusion. No signs of an inflammatory and/or allergic reaction were observed in any of the cases.

CONCLUSION

The obtained results show that implants made of a 90/10% platinum-gold alloy and 999.9 fine platinum have similar biointegration in terms of morphological features during 6 months of the follow-up period.

Keywords:

lagophthalmos

facial palsy

gold weight implant

platinum weight implant

implant capsule

morphological study

Authors:

Y.O. Grusha

I.M. Sechenov First Moscow State Medical University (Sechenov University);
Krasnov Research Institute of Eye Diseases

ORCID: 0000-0002-6461-8243

A.A. Fedorov

Moscow Regional Scientific Research Institute of Obstetrics and Gynecology

ORCID: 0000-0003-2590-5087

V.A. Sheptulin

Research Institute of Eye Diseases

E.I. Fettser

Krasnov Research Institute of Eye Diseases;
Sechenov First Moscow State Medical University

ORCID: 0000-0002-3729-7480

Received:

31.05.2020

Accepted:

08.06.2020

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