Pain syndrome after surgical treatment of breast cancer

N.E. Manturova

Pirogov Russian National Research Medical University;
Institute of Plastic Surgery and Cosmetology

SPIN RSCI: 5232-0412
Scopus AuthorID: 55461712100
ORCID: 0000-0003-4281-1947

V.E. Karasev

Omsk State Medical University;
Clinical Oncology Dispensary

A.Kh. Ismagilov

Republican Clinical Oncology Dispensary

Pain syndrome after surgical treatment of breast cancer

Authors:

N.E. Manturova, V.E. Karasev, A.Kh. Ismagilov

More about the authors

Journal: Plastic Surgery and Aesthetic Medicine. 2022;(4): 35‑40

DOI: 10.17116/plast.hirurgia202204135

Downloaded: 198

To cite this article:

Manturova NE, Karasev VE, Ismagilov AKh. Pain syndrome after surgical treatment of breast cancer. Plastic Surgery and Aesthetic Medicine. 2022;(4):35‑40. (In Russ., In Engl.)
https://doi.org/10.17116/plast.hirurgia202204135

Доказательная гастроэнтерология: pro et contra

Актуальные вопросы педиатрической практики

Использование инфографики авторами научных работ

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OBJECTIVE

To identify the features of pain syndrome before and after various surgical treatments of breast cancer, choose the optimal method and improve the quality of life in working-age patients.

MATERIAL AND METHODS

We followed-up 353 women with breast cancer before and for 5 years after surgery using the visual analogue scale, the Hospital Anxiety and Depression Scale and the SF-36 questionnaire.

RESULTS

Pain bothered 89% of patients within 6 months after surgical treatment. The most intense pain syndrome (8±1.3 points) was observed in early postoperative period. Moderate and severe pain syndrome (up to 7±1.2 points) was also observed after installation of expander. Insertion of implant decreased pain syndrome. There was weak correlation between pain syndrome and anxiety (G=0.16, p=0.027), pain syndrome and depression (G=0.18, p=0.019). Maximum scores were observed in the mastectomy group. Mean cumulative SF-36 score decreased by 15.9% (p=0.074) over 5-year follow-up in the mastectomy group. This value increased by 18.3% and 20.1% in the simultaneous and delayed reconstruction groups, respectively.

CONCLUSION

Reconstructive plastic surgery reduced severity of pain and improved psycho-emotional state of women that positively affects quality of life.

Keywords:

postmastectomy syndrome

pain

breast cancer

reconstructive surgery

Authors:

N.E. Manturova

Pirogov Russian National Research Medical University;
Institute of Plastic Surgery and Cosmetology

SPIN RSCI: 5232-0412
Scopus AuthorID: 55461712100
ORCID: 0000-0003-4281-1947

V.E. Karasev

Omsk State Medical University;
Clinical Oncology Dispensary

A.Kh. Ismagilov

Republican Clinical Oncology Dispensary

Received:

22.06.2022

Accepted:

20.07.2022

List of references:

Imangaliyev EA. Experience in the application of modified mastectomy with transpectoral lymphodissection. Oncology and Radiology of Kazakhstan. 2016;3(41):193-194. (In Russ.).
Obmanov IV, Yarigin ML, Shmirev VI, Yarigin LM. Neurological disturbances in post-surgical patients with breast cancer. S.S. Korsakov Journal of Neurology and Psychiatry. 2015;115(8):42-44. (In Russ.). https://doi.org/10.17116/jnevro20151158142-44
Afanasyeva KV. Quality of life of patients suffering from breast cancer after axillary lymphadenectomy in comparison with the quality of life of women after a biopsy of the sentinel lymph node. Comparative analysis. Bulletin of the RONC named after N.N. Blokhin RAMS. 2017;28(1-2):45-52. (In Russ.).
Dunne M, Keenan K. CE: Late and long-term sequelae of breast cancer treatment. Am J Nurs. 2016;116(6):36-45. https://doi.org/10.1097/01.NAJ.0000484223.07306.45
Jung BF, Ahrendt GM, Oaklander AL, Dworkin RH. Neuropathic pain following breast cancer surgery: proposed classification and research update. Pain. 2003;104(1):1-13. https://doi.org/10.1016/s0304-3959(03)00241-0
Filonenko EV, Kaprin AD, Polyak MA, Troshenkov EA, Malik DS. Rehabilitation of Cancer Patients After Surgical and Combined Treatment for Breast Cancer. Physical and Rehabilitation Medicine, Medical Rehabilitation. 2021;3(2):178-186. (In Russ.). https://doi.org/10.36425/rehab70778
Wang L, Guyatt GH, Kennedy SA, et al. Predictors of persistent pain after breast cancer surgery: A systematic review and meta-analysis of observational studies. CMAJ. 2016;188(14):352-361. First published July 11, 2016. https://doi.org/10.1503/cmaj.151276
Stakhanov ML, Velsher LZ, Savin AA. Postmastectomy syndrome: pathogenesis, classification. Russian Journal of Oncology. 2006;1:24-32. (In Russ).
Vilholm OJ, Sindrup SH. The postmastectomy pain syndrome: An epidemiological study on the prevalence of chronic pain after surgery for breast cancer. Br J Cancer. 2008;99(4):604-610. https://doi.org/10.1038/sj.bjc.6604534
Shikhkerimov RK, Velsher LZ, Savin AA, Stakhanov ML, Stulin ID, Savin LA, Koichakaeva AS, Strazhev SV, Karandeeva TV. Clinical variants of postmastectomy syndrome. Proceedings of the scientific and practical conference “New technologies in the diagnosis and treatment of breast cancer and skin melanoma”. M. 2010;48-49. (In Russ.).
Maslyakov VV, Levina VA, Nakayeva EYu. Modern aspects of medico-social rehabilitation of patients with mammary gland cancer. Medical and Social Expert Evaluation and Rehabilitation. 2015;18(1):14-17. (In Russ). https://doi.org/10.17816/MSER35837
Magomedov MM, Khalitov IA, Mikhailova BI, Tidulaeva PR, Koichakaeva AS, Malikova AG, Akhmedova PG. Psychoemotional problems of patients with postmastectomy syndrome. Basic Research. 2009;9:52-53. (In Russ).
Vanesyan AS. The investigation of the influence of the breast reconstruction on the quality of life of patients with central-medial breast cancer. Creative Surgery and Oncology. 2011;4:42-47. (In Russ).

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