Successful treatment with sertaconazole of microsporia in a patient infected from an elephant

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L.P. Kotrekhova

Sankt-Peterburg Academy of Post-Diploma Education;
P.N. Kashkin Research Institute of Medical Mycology

G.A. Chilina

NII meditsinskoĭ mikologii Sankt-Peterburgskoĭ akademii poslediplomnogo obrazovaniia;
Sankt-Peterburgskaia gosudarstvennaia pediatricheskaia meditsinskaia akademiia

I.M. Pchelin

North-Western State Medical University named after I.I. Mechnikov, Saint-Petersburg, Russia

E.N. Tsurupa

«North-Western State Medical University Named After I.I Mechnikov» Under The Ministry Of Public Health Of The Russian Federation, Saint-Petersburg, Russia, 191015

K.I. Raznatovskiĭ

P.N. Kashkin Research Institute of Medical Micology State educational institution of higher professional education "Sankt Peterburg Medical Academy of Postgraduate Education", Federal Agency for Healthcare and Social Development

N.V. Vasil'eva

P.N. Kashkin Research Institute of Medical Micology State educational institution of higher professional education "Sankt Peterburg Medical Academy of Postgraduate Education", Federal Agency for Healthcare and Social Development

Successful treatment with sertaconazole of microsporia in a patient infected from an elephant

Authors:

L.P. Kotrekhova, G.A. Chilina, I.M. Pchelin, E.N. Tsurupa, K.I. Raznatovskiĭ, N.V. Vasil'eva

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Journal: Russian Journal of Clinical Dermatology and Venereology. 2019;18(2): 154‑159

DOI: 10.17116/klinderma201918021154

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To cite this article:

Kotrekhova LP, Chilina GA, Pchelin IM, Tsurupa EN, Raznatovskiĭ KI, Vasil'eva NV. Successful treatment with sertaconazole of microsporia in a patient infected from an elephant. Russian Journal of Clinical Dermatology and Venereology. 2019;18(2):154‑159. (In Russ., In Engl.)
https://doi.org/10.17116/klinderma201918021154

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Microsporia of skin and scalp is one of the most common clinical forms of ringworm in the Russian Federation. The main sources of microsporia infection are cats and dogs, less often rabbits, small rodents and goats. It is presented rare case report (perhaps, the first one) of a 32-year-old man infection with microsporia from an Indian elephant on Phuket Island in Southeast Asia. Microsporum canis as the most common cause of microsporia resulted skin mycosis in this case. The course of microsporia was characterized by a large number of pustules. Molecular genetic analysis of M. canis isolated from the patient confirmed identity of its genotype with the genotypes of local strains of M. canis. Those strains were previously isolated from people who were infected by cats in the North-West region, St. Petersburg and Leningrad region. Therapy with sertaconazole and griseofulvin was highly effective. Currently, wide range of topical antifungal drugs is available. Therapy with sertaconazole is very effective for microsporia due to unique structure of the active molecule followed by fungicidal effect and wide spectrum of action on the most of pathogens of skin mycoses.

Keywords:

microsporia

Microsporum canis

Indian elephant

sertaconazole

Authors:

L.P. Kotrekhova

Sankt-Peterburg Academy of Post-Diploma Education;
P.N. Kashkin Research Institute of Medical Mycology

G.A. Chilina

NII meditsinskoĭ mikologii Sankt-Peterburgskoĭ akademii poslediplomnogo obrazovaniia;
Sankt-Peterburgskaia gosudarstvennaia pediatricheskaia meditsinskaia akademiia

I.M. Pchelin

North-Western State Medical University named after I.I. Mechnikov, Saint-Petersburg, Russia

E.N. Tsurupa

«North-Western State Medical University Named After I.I Mechnikov» Under The Ministry Of Public Health Of The Russian Federation, Saint-Petersburg, Russia, 191015

K.I. Raznatovskiĭ

P.N. Kashkin Research Institute of Medical Micology State educational institution of higher professional education "Sankt Peterburg Medical Academy of Postgraduate Education", Federal Agency for Healthcare and Social Development

N.V. Vasil'eva

P.N. Kashkin Research Institute of Medical Micology State educational institution of higher professional education "Sankt Peterburg Medical Academy of Postgraduate Education", Federal Agency for Healthcare and Social Development

List of references:

Klimko NN. Mycoses: diagnosis and treatment. Guidelines for doctors. The 3rd prod. reslave. and additional. M. 2017;272. (In Russ.)
Kubanova AA, Potekaev NC, Potekaev NN. Manual of practical mycology. M. 2001;144. (In Russ.)
Kakourou T, Uksal U. Guidelines for the management of tinea capitis in children. Padiatr Dermtol 2010;27(3):226-228. https://doi.org/10.1111/j.1525-1470.2010.01137.x
Kotrekhova LP, Raznatovskiy KI, Vashkevich AA. Features of the current mycoses of the skin at the present stage and their rational therapy. Dermatologiya. Prilozhenie k zhurnalu Consilium Medicum. 2014;(1):30-34. (In Russ.)
Medvedeva TV, Leina LM, Chilina GA, Bogomolova TS, Kotrekhova LP, Aleksandrova IB. Microsporia: rare clinical cases. Russian Journal of Clinical Dermatology and Venereology = Klinicheskaya dermatologiya i venerologiya. 2012;10(4):94-101. (In Russ.)
Seyedmousavi S, Bosco S, Hoog S, et al. Fungal infections in animals: a patchwork of different situations. Medical Mycology. 2018;56(1):165-187. https://doi.org/10.1093/mmy/myx104
Cafarchia C, Camarda A, Coccidi C, et al. Epidemiology and risk factors for dermatophytoses in rabbit farms. Medical Mycology. 2010 Nov;48(Issue 7): 975-980. https://doi.org/10.3109/13693781003652620
Qiao X, Hu J, Wu D, et al. Isolation and identification of microsporum canis from asian elephants (elephant maximus) in the Chongqing zoo, China. J Zoo Wildlife Med. 47(3):844-845. https://doi.org/10.1638/2014-0213.1
Qiao X, Wei L, Yang Y, et al. The Characteristics of New Zealand Rabbit Model for Infection with Pathogens of Fungal Skin Disease in Asian Elephants in Chongqing. J Anim Veterin Adv. 2014;13:917-921.
Dokazatel’nij opyt terapii mikozov kozhi. Posobie dlya vrachey. Izd. 2-e s ispravl. Pod red. Sergeeva AYu. M. 2016;40. (In Russ.)
Figueras MJ, Cano JF, Gurmo J. Ultrastructural alterations produced by sertaconazole on several opportunistic pathogenic fungi. Journal of Medical and Veterinary Mycology. 1995 Nov;33(Issue 6):395–401. https://doi.org/10.1080/02681219580000761
Carrillo-Muñoz AJ, Fernandez-Torres B, Guarro J. In vitro antifungal activity of sertaconazole against 309 dermatophyte clinical isolates. J Chemother. 2003;15(6):555-557. https://doi.org/10.1179/joc.2003.15.6.555
Guarro J, Figueras MJ, Cano J. Alterations Produced by Sertaconazole on the Morphology and Ultrastructure of Candida albicans: Sertaconazol‐bedingte Veranderungen der Morphologie und Ultrastruktur von Candida albicans. Mycoses. 1989;32(6):283-295. https://doi.org/10.1111/j.1439-0507.1989.tb02246.x
Van Zuuren EJ, Fedorowicz Z, El-Gohary M. Evidence-based topical treatments for tinea cruris and tinea corporis: a summary of a Cochrane systematic review. Br J Dermatol. 2015;172(3):616-641. https://doi.org/10.1111/bjd.13441
Rotta I, Ziegelmann PK, Otuki MF. Efficacy of topical antifungals in the treatment of dermatophytosis: a mixed-treatment comparison meta-analysis involving 14 treatments. JAMA Dermatol. 2013;149(3):341-349. https://doi.org/10.1001/jamadermatol.2013.1721
Kotrekhova LP, Raznatovsky KI, Tzurupa EN, Kungurtseva EK, Koryukina EB, Nesterov SN, Skurikhina ME, Prozherin SV. Experience of effective use of sertaconazole in the treatment of dermatomycoses. Probl med mikol. 2017;19(1):18-23. (In Russ.)

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