Is psychological stress a risk factor for ulcerative colitis? (in Russian only)

G.R. Bikbavova

Omsk State Medical University of the Ministry of Health of the Russia, Omsk, Russia

M.A. Livzan

Omsk State Medical Academy

V.I. Sovalkin

Omsk State Medical University of the Ministry of Health of the Russia, Omsk, Russia

D.V. Turchaninov

Kafedra akusherstva i ginekologii fakul'teta poslediplomnogo obrazovaniia Omskoĭ gosudarstvennoĭ meditsinskoĭ akademii

A.P. Akhramovich

Regional Clinical Hospital, Omsk, Russia

Is psychological stress a risk factor for ulcerative colitis? (in Russian only)

Authors:

G.R. Bikbavova, M.A. Livzan, V.I. Sovalkin, D.V. Turchaninov, A.P. Akhramovich

More about the authors

Journal: Russian Journal of Evidence-Based Gastroenterology. 2019;8(2): 37‑42

DOI: 10.17116/dokgastro2019802137

Downloaded: 96

To cite this article:

Bikbavova GR, Livzan MA, Sovalkin VI, Turchaninov DV, Akhramovich AP. Is psychological stress a risk factor for ulcerative colitis? (in Russian only). Russian Journal of Evidence-Based Gastroenterology. 2019;8(2):37‑42. (In Russ., In Engl.)
https://doi.org/10.17116/dokgastro2019802137

Кардиологические дебаты — VI. Версия 2.0

Доказательная гастроэнтерология: pro et contra

Актуальные вопросы педиатрической практики

Использование инфографики авторами научных работ

Close metadata

Recommended articles:

Analysis of p53 protein expression and formation of dark neurons in the hippocampus of rats during septoplasty modeling. Russian Rhinology. 2023;(1):27-36

Influence of significant stressful events on the course of primary cephalalgia. Russian Journal of Pain. 2023;(1):26-32

Extraintestinal manifestations of inflammatory bowel disease. Russian Journal of Evidence-Based Gastroenterology. 2023;(1):93-98

Anesthesia-dependent stress responses in pediatric anorectal abnormalities. Russian Journal of Anesthesiology and Reanimatology. 2023;(2):58-64

Features of the mental state of doctors of various specialties during the COVID-19 pandemic. Russian Journal of Preventive Medicine and Public Health. 2023;(3):81-90

The role of nutrition in the prevention and treatment of inflammatory bowel disease. Russian Journal of Preventive Medicine and Public Health. 2023;(3):123-129

Nosogenic psychosomatic disorders in patients with skin diseases. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;(4-2):36-43

The role of the mediator and hormonal links of the sympathetic-adrenal system in the anxiolytic effect of close to physiological doses of L-thyroxine under stress. S.S. Korsakov Journal of Neurology and Psychiatry. 2023;(6):106-112

Individual and contextual conditions of behavioral risk factors’ formation in students of food technology specialty. Russian Journal of Preventive Medicine and Public Health. 2023;(7):67-73

Efficacy of perioperative analgesia in children with anorectal malformations. Russian Journal of Anesthesiology and Reanimatology. 2023;(4):19-26

Objective — to assess the impact of emotional and mental stress, duration of sleep and bedtime on the occurrence of ulcerative colitis (UC) in the population of the Western Siberia. Material and methods. A retrospective case-control study included 81 patients with ulcerative colitis and 39 healthy respondents. Mental tension and stress severity prior to the diagnosis of ulcerative colitis were compared with the same variables in healthy respondents. Effect of sleep duration on the occurrence of ulcerative colitis was analyzed using a specific questionnaire to specify bedtime and duration of sleep. Results. Emotional and mental stress before the onset of clinical symptoms was noted in all patients and over 50% of them associate debut of disease with previous stress. Patients with UC significantly more often characterized themselves as nervous people experiencing great stress during daily activity and communication with other persons before the onset of clinical symptoms. These patients felt complete physical and mental exhaustion in the evening compared with healthy respondents. Duration of sleep and bedtime were not the predictors of ulcerative colitis in the population of the Western Siberia. Conclusion. Stress is an essential predictor and possible potential trigger of ulcerative colitis. Duration of sleep and bedtime do not affect the occurrence of ulcerative colitis.

Keywords:

ulcerative colitis

stress

emotional and mental stress

duration of sleep

Authors:

G.R. Bikbavova

Omsk State Medical University of the Ministry of Health of the Russia, Omsk, Russia

M.A. Livzan

Omsk State Medical Academy

V.I. Sovalkin

Omsk State Medical University of the Ministry of Health of the Russia, Omsk, Russia

D.V. Turchaninov

Kafedra akusherstva i ginekologii fakul'teta poslediplomnogo obrazovaniia Omskoĭ gosudarstvennoĭ meditsinskoĭ akademii

A.P. Akhramovich

Regional Clinical Hospital, Omsk, Russia

List of references:

Ding T, Schloss PD. Dynamics and associations of microbial community types across the human body. Nature. 2014;509(7500):357-360. https://doi.org/10.1038/nature13178
Costello EK, Lauber CL, Hamady M, Fierer N, Gordon JI, Knight Â R. Bacterial community variation in human body habitats across space and time. Science. 2009;326(5960):1694-1697. https://doi.org/10.1126/science.1177486
Leslie JL, Young VB. The rest of the story: the microbiome and gastrointestinal infections. Current Opinion in Microbiology. 2015;23:121-125. https://doi.org/10.1016/j.mib.2014.11.010
Cryan JF, Dinan TG. Mind-altering microorganisms: the impact of the gut microbiota on brain and behavior. Nature Reviews Neuroscience. 2012;13(10):701-712. https://doi.org/10.1038/nrn3346
Wells JM, Brummer RJ, Derrien M, MacDonald TT, Troost F, Cani PD, Theodorou V, Dekker J, MÃ©heust A, de Vos WM, Mercenier A, Nauta A, Garcia-Rodenas CL. Homeostasis of the gut barrier and potential biomarkers. American Journal of Physiology: Gastrointestinal and Liver Physiology. 2017;312(3):171-193. https://doi.org/10.1152/ajpgi.00048.2015
Turnbaugh PJ, Hamady M, Yatsunenko T, Cantarel BL, Duncan Â A, Ley RE, Sogin ML, Jones WJ, Roe BA, Affourtit JP, Egholm M, Henrissat B, Heath AC, Knight R, Gordon JI. A core gut microbiome in obese and lean twins. Nature. 2009;457:480-484. https://doi.org/10.3410/f.1157610.617807
Oâ€™Keefe SJ. Diet, microorganisms and their metabolites, and colon cancer. Nature Reviews Gastroenterology and Hepatology. 2016;13:691-706. https://doi.org/10.1038/nrgastro.2016.165
Russell SL, Gold MJ, Hartmann M, Willing BP, Thorson L, Wlodarska M, Gill N, Blanchet MR, Mohn WW, McNagny KM, Finlay BB. Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma. EMBO Reports. 2012;13:440-447. https://doi.org/10.1038/embor.2012.32
Luna RA, Foster JA. Gut brain axis: diet microbiota interactions and implications for modulation of anxiety and depression. Current Opinion in Biotechnology. 2015;32:35-41. https://doi.org/10.1016/j.copbio.2014.10.007
Mackos AR, Maltz R, Bailey MT. The role of the commensal microbiota in adaptive and maladaptive stressor-induced immunomodulation. Hormones and Behavior. 2017;88:70-78. https://doi.org/10.1016/j.yhbeh.2016.10.006
Bernstein CN, Singh S, Graff LA, Walker JR, Miller N, Cheang Â M. A Prospective Population-Based Study of Triggers of Symptomatic Flares in IBD. American Journal of Gastroenterology. 2010;105:1994-2002. https://doi.org/10.1038/ajg.2010.140
Galley JD, Nelson MC, Yu Z, Dowd SE, Walter J, Kumar PS, LyteÂ M, Bailey MT. Exposure to a social stressor disrupts the community structure of the colonic mucosa-associated microbiota. BMC Microbiology. 2014;14:189. https://doi.org/10.1186/1471-2180-14-189
Bailey MT, Dowd SE, Parry NMA, Galley JD, Schauer DB, Lyte Â M. Stressor exposure disrupts commensal microbial populations in the intestines and leads to increased colonization by citrobacter rodentium. Infection and Immunity. 2010;78:1509- 1519. https://doi.org/10.1128/iai.00862-09
Bailey MT, Dowd SE, Galley JD, Hufnagle AR, Allen RG, Lyte Â M. Exposure to a social stressor alters the structure of the intestinal microbiota: Implications for stressor-induced immunomodulation. Brain, Behavior, and Immunity. 2011;25:397-407. https://doi.org/10.1016/j.bbi.2010.10.023
Maunder RG, Levenstein S. The role of stress in the development and clinical course of inflammatory bowel disease: epidemiological evidence. Current Molecular Medicine. 2008;8:247-252. https://doi.org/10.2174/156652408784533832
Mawdsley JE, Rampton DS. Psychological stress in IBD: new insights into pathogenic and therapeutic implications. Gut. 2005;54:1481-1491. https://doi.org/10.1136/gut.2005.064261
Bonaz BL, Bernstein CN. Brain-gut interactions in inflammatory bowel disease. Gastroenterology. 2013;144:36-49. https://doi.org/10.1053/j.gastro.2012.10.003
Xinghua G, Qiuhua C, Yan C, Dandan Z, Zhuo W, Hongbao Y, Qijin W, Linjun Y, Yue W, Yanting L, Xianjing L, Yun W, Jin-SongÂ B, Dongdong S, Lingyi K, Lutz B. Chronic stress promotes colitis by disturbing the gut microbiota and triggering immune system response. PNAS: Proceedings of the National Academy of Sciences of the United States of America. 2018;115(13):2960-2969. https://doi.org/10.1073/pnas.1806622115
Timoshenko SO, Nazarov SB. Complex characteristics of night sleep of high school students and medical students. Zdorov’e i obrazovanie v XXI veke. 2007;9(3):285. (In Russ.)
Ivashkin VT, Shelygin YuA, Khalif IL, Belousova EA, Shifrin OS, Abdulganieva DI, Abdulkhakov RA, Alekseeva OP, Alekseenko SA, Achkasov SI, Baranovskii AYu, Bolikhov KV, Valuiskikh EYu, Vardanyan AV, Veselov AV, Veselov VV, Golovenko AO, Golovenko OV, Grigor’ev EG, Gubonina IV, Zhigalova TN, Kashnikov VN, Kizova EA, Knyazev OV, Kostenko NV, Kulyapin AV, Morozova NA, Murav’ev AV, Nizov AA, Nikitina NV, Nikolaeva NN, Nikulina NV, Odintsova AKh, Osipenko MF, Pavlenko VV, Parfenov AI, Poluektova EA, Potapov AS, Rumyantsev VG, Svetlova IO, Sitkin SI, Timerbulatov VM, Tkachev AV, Tkachenko EI, Frolov SA, Khubezov DA, Chashkova EYu, Shapina MV, Shchukina OB, Yakovlev AA. Clinical recommendations of the Russian gastroenterological Association and Association of coloproctologists of Russia for the diagnosis and treatment of ulcerative colitis. Koloproktologiya. 2017;1:6-30. (In Russ.)
Erofeev YuV, Boldyreva MS, Turchaninov DV. Organizatsiya i metodika provedeniya sotsiologicheskikh issledovanii zdorov’ya sel’skogo naseleniya dlya informatsionnogo obespecheniya sistemy sotsial’no-gigienicheskogo monitoringa. Metodicheskie rekomendatsii. Omsk: Izdatel’stvo FGU TsGSEN Omskoi oblasti, 2004. (In Russ.)
Reeder LG, Chapman JM, Coulson AH. Socioenvironmental stress, tranquilizers and cardiovascular disease. Proceedings of the Excerpta Medica International Congress Series. 1968;182:226-238. https://doi.org/10.1093/oxfordjournals.aje.a120605

Close metadata