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S.N. Tolpygina

National Medical Research Center for Therapy and Preventive Medicine

A.V. Zagrebelny

National Medical Research Center for Therapy and Preventive Medicine

M.I. Chernysheva

City Polyclinic No. 218

N.P. Kutishenko

National Medical Research Center for Therapy and Preventive Medicine

Yu.V. Lukina

National Medical Research Center for Therapy and Preventive Medicine

V.P. Voronina

National Medical Research Center for Therapy and Preventive Medicine

N.A. Dmitrieva

National Medical Research Center for Therapy and Preventive Medicine

O.V. Lerman

National Medical Research Center for Therapy and Preventive Medicine

M.M. Loukianov

National Medical Research Center for Therapy and Preventive Medicine

E.Yu. Okshina

National Medical Research Center for Therapy and Preventive Medicine

N.E. Parsadanyan

City Polyclinic No. 218

S.Yu. Martsevich

National Medical Research Center for Therapy and Preventive Medicine

O.M. Drapkina

National Medical Research Center for Therapy and Preventive Medicine;
A.I. Yevdokimov Moscow State University of Medicine and Dentistry

Comorbidity and long-term survival of patients suffered from acute cerebrovascular accident based on the REGION-M registry

Authors:

S.N. Tolpygina, A.V. Zagrebelny, M.I. Chernysheva, N.P. Kutishenko, Yu.V. Lukina, V.P. Voronina, N.A. Dmitrieva, O.V. Lerman, M.M. Loukianov, E.Yu. Okshina, N.E. Parsadanyan, S.Yu. Martsevich, O.M. Drapkina

More about the authors

Journal: Russian Journal of Preventive Medicine. 2023;26(11): 64‑68

DOI: 10.17116/profmed20232611164

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COMORBIDITY AND LONG-TERM SURVIVAL OF PATIENTS SUFFERED FROM ACUTE CEREBROVASCULAR ACCIDENT BASED ON THE REGION-M REGISTRY
COMORBIDITY AND LONG-TERM SURVIVAL OF PATIENTS SUFFERED FROM ACUTE CEREBROVASCULAR ACCIDENT BASED ON THE REGION-M REGISTRY

To cite this article:

Tolpygina SN, Zagrebelny AV, Chernysheva MI, Kutishenko NP, Lukina YuV, Voronina VP, Dmitrieva NA, Lerman OV, Loukianov MM, Okshina EYu, Parsadanyan NE, Martsevich SYu, Drapkina OM. Comorbidity and long-term survival of patients suffered from acute cerebrovascular accident based on the REGION-M registry. Russian Journal of Preventive Medicine. 2023;26(11):64‑68. (In Russ.)
https://doi.org/10.17116/profmed20232611164

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OBJECTIVE

To study the impact of comorbid diseases on long-term survival of patients who have suffered acute cerebrovascular accident (ACVA/CVA).

MATERIAL AND METHODS

REGION-M outpatient register included 684 patients with confirmed ACVA (stroke or transitory ischemic attack) diagnosis attached to City Polyclinic №218, signed out from Inozemtsev City Clinical Hospital for the period from 01.01.12 yr. to 30.04.17 yr. The outpatient observation stage from 2017 to 2022 yr. was equal 5.5 (2.4—7.0) years. «Death from all causes» was chosen as a final point.

RESULTS

In single-factor analysis, the presence of ischemic heart disease (p<0.0001), previous myocardial infarction (p<0.0001), the presence of diabetes mellitus (p<0.05) and obesity (p<0.01) had a negative effect on the prognosis. In multi-factor analysis, including in addition to comorbid diseases, sex and age, only myocardial infarction in the history (RA of death 1.009 (95% CI 1.004—1.014, p<0.001) retained statistical significance.

CONCLUSION

In patients who have suffered acute cerebrovascular accident the presence of myocardial infarct in the history worsened the long-term survival

Keywords:

cerebrovascular accident
comorbid diseases
register
long-term survival
mortality

Authors:

S.N. Tolpygina

National Medical Research Center for Therapy and Preventive Medicine

A.V. Zagrebelny

National Medical Research Center for Therapy and Preventive Medicine

M.I. Chernysheva

City Polyclinic No. 218

N.P. Kutishenko

National Medical Research Center for Therapy and Preventive Medicine

Yu.V. Lukina

National Medical Research Center for Therapy and Preventive Medicine

V.P. Voronina

National Medical Research Center for Therapy and Preventive Medicine

N.A. Dmitrieva

National Medical Research Center for Therapy and Preventive Medicine

O.V. Lerman

National Medical Research Center for Therapy and Preventive Medicine

M.M. Loukianov

National Medical Research Center for Therapy and Preventive Medicine

E.Yu. Okshina

National Medical Research Center for Therapy and Preventive Medicine

N.E. Parsadanyan

City Polyclinic No. 218

S.Yu. Martsevich

National Medical Research Center for Therapy and Preventive Medicine

O.M. Drapkina

National Medical Research Center for Therapy and Preventive Medicine;
A.I. Yevdokimov Moscow State University of Medicine and Dentistry

Received:

10.07.2023

Accepted:

01.08.2023

List of references:

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  3. Martsevich SYu, Kutishenko NP, Suvorov AYu, et al. The study of anamnestic factors and their role in estimation of short-term (in-hospital) prognosis in patient underwent brain stroke or transient ischemic attack, by the data LIS-2 registry. Rossijskij kardiologicheskij zhurnal. 2015;6(122):14-19. (In Russ). https://doi.org/10.15829/1560-4071-2015-6-14-19
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  6. Tolpygina SN, Martsevich SYu, Deev AD. The influence of concomitant diseases on a long-term prognosis in patients with chronic ischemic heart disease according to the PROGNOZ IBS register. Racional’naja farmakoterapija v kardiologii. 2015;11(6):571-576. (In Russ.). https://doi.org/10.20996/1819-6446-2015-11-6-571-576
  7. Voronina VP, Zagrebelnyi AV, Lukina YuV, et al. Features of cerebral stroke course in patients with diabetes mellitus according to the REGION-M register. Kardiovaskuljarnaja terapija i profilaktika. 2019;18(5):60-65. (In Russ.). https://doi.org/10.15829/1728-8800-2019-5-60-65
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